(data stored in ACNUC7421 zone)

HOGENOM: CLBOT1_1_PE1015

ID   CLBOT1_1_PE1015                      STANDARD;      PRT;   451 AA.
AC   CLBOT1_1_PE1015; A5I0M8; A7G2E1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Sensor histidine kinase; EC=2.7.3 -;SubName:
DE   Full=Two-component sensor kinase;Flags: Precursor; (CLBOT1_1.PE1015).
GN   OrderedLocusNames=CBO1036, CLC_1089;
OS   CLOSTRIDIUM BOTULINUM A STR. ATCC 3502.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=413999;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CLBOT1_1.PE1015.
CC       Clostridium botulinum A str. ATCC 3502, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A5I0M8_CLOBH
CC   -!- CATALYTIC ACTIVITY: ATP + protein L-histidine = ADP + protein N-
CC       phospho-L-histidine.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (By
CC       similarity).
CC   -!- SIMILARITY: Contains 1 histidine kinase domain.
CC   -!- GENE_FAMILY: HOG000245618 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A5I0M8; A7G2E1; -.
DR   EMBL; CP000727; ABS38124.1; -; Genomic_DNA.
DR   EMBL; AM412317; CAL82589.1; -; Genomic_DNA.
DR   RefSeq; YP_001253567.1; NC_009495.1.
DR   RefSeq; YP_001386956.1; NC_009698.1.
DR   ProteinModelPortal; A5I0M8; -.
DR   STRING; A5I0M8; -.
DR   GeneID; 5185291; -.
DR   GeneID; 5398249; -.
DR   GenomeReviews; AM412317_GR; CBO1036.
DR   GenomeReviews; CP000727_GR; CLC_1089.
DR   KEGG; cbh:CLC_1089; -.
DR   KEGG; cbo:CBO1036; -.
DR   OMA; KRWLANI; -.
DR   ProtClustDB; CLSK882849; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:two-component sensor activity; IEA:InterPro.
DR   GO; GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
DR   InterPro; IPR003594; ATPase-like_ATP-bd.
DR   InterPro; IPR003660; HAMP_linker_domain.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   InterPro; IPR003661; Sig_transdc_His_kin_sub1_dim/P.
DR   InterPro; IPR005467; Sig_transdc_His_kinase_core.
DR   InterPro; IPR009082; Sig_transdc_His_kinase_dimeric.
DR   Gene3D; G3DSA:3.30.565.10; ATP_bd_ATPase; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF55874; ATP_bd_ATPase; 1.
DR   SUPFAM; SSF47384; His_kin_homodim; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   HOGENOMDNA; CLBOT1_1.PE1015; -.
KW   sensor histidine kinase;
KW   ATP-binding; Complete proteome; Kinase; Membrane; Nucleotide-binding;
KW   Phosphoprotein; Signal; Transferase; Transmembrane;
KW   Two-component regulatory system.
SQ   SEQUENCE   451 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MHTIRKRLSI LFVICSVAGI LLVTLFVNAT INNKFDAYIV DVQDKRYQRI VSYFEEVYKA
     QGKWTKNSGV ELMHEAHMGN YCLTLLDINK KTIWGMNPND IRLNTMPVKD RGVYNTKTFE
     IKSEGKVVGY VGIGQYSSLL LSEEDISFKT SINKSIVASG ILTLVIIITI SLYFSKQFSI
     PIKEVANLSV NLSKGDFDGK SSVESNIEEL ENLRKSVNIL AEKLKHQDSI RRRLVSDISH
     EIRTPLNVLQ NNLEAMIDGV LPVTEERLNC LNEEVVRFGR LLNNLNVLKE FESESIKLNF
     QKIFLDELIA DICSDFYAIA ENKNIKLQYH IENHEDYSIT GDRDRLKQVF INLLSNALKF
     TEDGGEVLIK IYKSDKNIVV EVKDNGVGIK KEDLPFIFER LYRGDKSRHQ FKGNGIGLTI
     VKNILQLHYA SIDLESEEGE GTTFKVYFHR M
//

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