(data stored in SCRATCH3701 zone)

HOGENOM6: CLOB6_3_PE7

ID   CLOB6_3_PE7                          STANDARD;      PRT;   826 AA.
AC   CLOB6_3_PE7; C3KXR3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (CLOB6_3.PE7).
GN   Name=gyrA; OrderedLocusNames=CLJ_B0007;
OS   CLOSTRIDIUM BOTULINUM BA4 STR. 657.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=515621;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CLOB6_3.PE7.
CC       Clostridium botulinum Ba4 str. 657, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C3KXR3_CLOB6
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C3KXR3; -.
DR   EMBL; CP001083; ACQ53857.1; -; Genomic_DNA.
DR   RefSeq; YP_002860879.1; NC_012658.1.
DR   STRING; C3KXR3; -.
DR   GeneID; 7879245; -.
DR   GenomeReviews; CP001083_GR; CLJ_B0007.
DR   KEGG; cbi:CLJ_B0007; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; CLOB6_3.PE7; -.
DR   PRODOM; CLOB6_3_PE7.
DR   SWISS-2DPAGE; CLOB6_3_PE7.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   826 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLNEGKILPV DVSKEMKKCY IDYAMSVIAG RALPDVRDGL KPVHRRIIYS MQGLGLAPEK
     GYRKCARIVG DVLGKYHPHG DTAVYEALVR MAQDFSIRYT LVDGHGNFGS VDGDGAAAMR
     YTEAKMSKIS MELIKDINKN TVDFIPNFDG EEEEPSVLPS RFPNLLVNGS AGIAVGMATN
     IPPHNLTEVI DGIIMLIENE DVSILDLMTK IKGPDFPTSG LIVGTRGIRE AYETGRGKVI
     IRAKAEIEEE KGKNRIIVTE IPYQVNKSKL IENMANLVKD KKINGISDIR DESDRQGMRI
     VIELKRDANP NIVLNQLYKH TKLQDTFGII MLALVNNQPQ VLNLKEILVN YVEFQKEVIR
     RRTRFDLDKA LARAHILEGL RIALDHIDEV IKLIRASKNT AEAKEGLMNN FNLSEKQAQA
     ILDMKLQRLT GLEREKIEEE YKELMEKISY FREILDKEEL VLSIIKEELI EIKNKYGDER
     KTEIVKGEHD IDIEDLIEDK KVIITLTHGG YIKRLDMDTY SSQKRGGKGI QATSTKQDDF
     IENMFVTSTH SIILFFTNRG KVYKLKAYEI PEAGRTAKGT NIVNLIPIEN NEKIQTVIGL
     KDIDDMKHFV MCTRNGIIKK TEIKKYSSIR KGGLNAINLR EDDELIDVKM TKGNNEIIIV
     TQNGYCIRFN EEDVRPMGRV ATGVKGITLR EDDKAVSMEV VLEDEALLSI SENGFGKRTD
     IEEYPIHRRG GKGVITYKIT DKTGPIVGAR FVKEDDELML VNSGDVAIRI NVSEISKTSR
     NAMGVKLMRT SEEEKIVAIA KIKSEDIIEE EILNEENLNE ENLNEE
//

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