(data stored in ACNUC7421 zone)

HOGENOM: CLOBH_1_PE1

ID   CLOBH_1_PE1                          STANDARD;      PRT;   448 AA.
AC   CLOBH_1_PE1; A5HXP7; A7FZS7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (CLOBH_1.PE1).
GN   Name=dnaA; OrderedLocusNames=CBO0001, CLC_0001;
OS   CLOSTRIDIUM BOTULINUM A STR. HALL.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=441771;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CLOBH_1.PE1.
CC       Clostridium botulinum A str. Hall, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:DNAA_CLOBH
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A5HXP7; A7FZS7; -.
DR   EMBL; CP000727; ABS36825.1; -; Genomic_DNA.
DR   EMBL; AM412317; CAL81555.1; -; Genomic_DNA.
DR   RefSeq; YP_001252553.1; NC_009495.1.
DR   RefSeq; YP_001385963.1; NC_009698.1.
DR   ProteinModelPortal; A5HXP7; -.
DR   STRING; A5HXP7; -.
DR   GeneID; 5187220; -.
DR   GeneID; 5400372; -.
DR   GenomeReviews; AM412317_GR; CBO0001.
DR   GenomeReviews; CP000727_GR; CLC_0001.
DR   KEGG; cbh:CLC_0001; -.
DR   KEGG; cbo:CBO0001; -.
DR   eggNOG; COG0593; -.
DR   OMA; CHTLNAL; -.
DR   ProtClustDB; PRK00149; -.
DR   BioCyc; CBOT36826:CBO0001-MON; -.
DR   BioCyc; CBOT441771:CLC_0001-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; CLOBH_1.PE1; -.
KW   chromosomal replication initiation protein;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
SQ   SEQUENCE   448 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNTHLTETWE KAINIIKGEL TEVSFNTWIK SINPISLENN SLKLAVPNDF TKGILESRYK
     DLIVNALKLL TSKKYNIDFI VTTEEKIEEN QKNHNNEKSN IVVNDEMSTM LNPKYTFDSF
     VIGNSNRFAH AASLAVAESP AKAYNPLFIY GGVGLGKTHL MHAIGHYILH NNPKSQVVYV
     SSEKFTNELI NSIKDDKNVE FRNKYRNIDI LLVDDIQFIA GKERTQEEFF HTFNALYEAN
     KQIIISSDRP PKEIPTLEDR LRSRFEWGLI ADIQAPDFET RMAILKKKAD VENLNIPNEV
     MVYIATKIKS NIRELEGALI RIVAFSSLTN KEISIDLASE ALKDIISSKQ TRQVTIDIIQ
     EVVANYYNLK IEDLKSARRT RNIAFPRQIA MYLSRKLTDM SLPKIGEEFG GRDHTTVIHA
     YEKISNNLKK DESLQNAIKE LNKRINQK
//

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