(data stored in SCRATCH3701 zone)

HOGENOM6: CLOSW_1_PE6

ID   CLOSW_1_PE6                          STANDARD;      PRT;   853 AA.
AC   CLOSW_1_PE6; D9QZV0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (CLOSW_1.PE6).
GN   OrderedLocusNames=Closa_0006;
OS   CLOSTRIDIUM SACCHAROLYTICUM WM1.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=610130;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CLOSW_1.PE6.
CC       Clostridium saccharolyticum WM1 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:D9QZV0_CLOSW
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D9QZV0; -.
DR   EMBL; CP002109; ADL02649.1; -; Genomic_DNA.
DR   RefSeq; YP_003820272.1; NC_014376.1.
DR   GeneID; 9505243; -.
DR   GenomeReviews; CP002109_GR; Closa_0006.
DR   KEGG; csh:Closa_0006; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; CLOSW_1.PE6; -.
DR   PRODOM; CLOSW_1_PE6.
DR   SWISS-2DPAGE; CLOSW_1_PE6.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   853 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MEPNIFDKVH DVDLKKTMEK SYIDYAMSVI VSRALPDVRD GLKPVQRRVL YSMIELNNGP
     DKPHRKCARI VGDTMGKYHP HGDSSIYGAL VNLAQEWSTR YPLVDGHGNF GSVDGDGAAA
     MRYTEARLSK ISMEMLADIN KDTVDFSPNF DETEREPDVL PSRYPNLLVN GTSGIAVGMA
     TNIPPHNLRE VISAVVHIID NQVEENRETT MEEILEIIKG PDFPTGATIL GKRGIEEAYR
     TGRGKIRVRA VSDIEAMANG KNRIIVTELP YMVNKARLIE KIAELVKDKK VDGITDLRDE
     SDRSGMRICI ELRRDANANV VLNQLIKHTQ LQDTFGVIML ALVKNSAGVL EPKVLNILQM
     LNYYLDHQKE VVTRRTRYDL NKAEERAHIL QGLLIALDNI DEVIRIIRGS ENVQAAKAEL
     MSRFGLSDVQ SQAIVDMRLR ALTGLEREKL ENEYRELEAR IAELKSILAD EKKLLGVIKE
     EISIISAKYG DDRRTSIGFD EFDMSMEDLI PDESTIVAMT KLGYIKRMSV DNFKNQNRGG
     RGIKGMQTID QDYIEDLMMT TTHHYLMFFT NTGRVYRLKT YMIPEGSRTS RGTAIVNLLQ
     MLPGESITAI IPMKEYDDDK FLFMATRNGM VKKTPMMEYA NVRKNGLQAI VLRENDELIE
     VKATDDTKDI FLVTKKGQCI RFHEKDVRIT GRVSMGVIGM KLNEDDQVVG MQKESQGPKL
     LIVSANGMGK RTPIEEFTPQ RRGGKGVLCY KITEKTGDIV GAKLVEDDHD LLLITTEGIV
     IRISVNDISV IGRNTSGVKL MNIDQDSDIT VASIAKVRDD GSKSDGEGLE ELDIIDEELP
     EEIKEMEDAP EEE
//

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