(data stored in SCRATCH3701 zone)

HOGENOM6: CODIP1_1_PE9

ID   CODIP1_1_PE9                         STANDARD;      PRT;   856 AA.
AC   CODIP1_1_PE9; Q6NKK9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (CODIP1_1.PE9).
GN   Name=gyrA; OrderedLocusNames=DIP0009;
OS   CORYNEBACTERIUM DIPHTHERIAE NCTC 13129.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=257309;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CODIP1_1.PE9.
CC       Corynebacterium diphtheriae NCTC 13129, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:Q6NKK9_CORDI
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q6NKK9; -.
DR   EMBL; BX248354; CAE48520.1; -; Genomic_DNA.
DR   RefSeq; NP_938418.1; NC_002935.2.
DR   HSSP; P09097; 1AB4.
DR   ProteinModelPortal; Q6NKK9; -.
DR   GeneID; 2648827; -.
DR   GenomeReviews; BX248353_GR; DIP0009.
DR   KEGG; cdi:DIP0009; -.
DR   NMPDR; fig|257309.1.peg.9; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; CODIP1_1.PE9; -.
DR   PRODOM; CODIP1_1_PE9.
DR   SWISS-2DPAGE; CODIP1_1_PE9.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   856 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDDLLGGDG YDRVHPIDLN EEMETSYIDY AMSVIVGRAL PEVRDGLKPV HRRILYAMYD
     SGYRPDRSYV KSARPVSDTM GQFHPHGDSA IYDTLVRLAQ DWNMRYPMVD GQGNFGSRGN
     DGPAAMRYTE CRLTPLAMEM VRDIRENTVD FSPNYDGKTQ EPDVLPSRVP NLLMNGSNGI
     AVGMATNIPP HNLRELGDAI FWLLDNPEAD EASALEACMK YVKGPDFPTA GQIVGSQGIN
     DAYTTGRGSI RMRGVTSIEE EGNRQIIVIT ELPYQVNPDN MISNIAEQVR DGKLAGISKI
     EDESSDRVGM RIVVTLKRDA VPRVVLNNLY KHSQLQTNFG ANMLSIVDGV PRTLRLDQML
     RHYVTHQIEV IVRRTQYRLD EAEKRAHILR GLVKALDMLD EVIALIRRSP TVDIARTGLM
     ELLTVDEIQA DAILAMQLRR LAALERQKIV DELAEIELEI ADYKDILARP ERQRAIVRDE
     LAEIVDKYGD DRRTQIIAAT GDVTEEDLIA RENVVVTITS TGYAKRTKVD AYKSQRRGGK
     GVRGAELKQD DVVRHFFVSS THDWILFFTN FGRVYRLKAY ELPEASRTAR GQHVANLLEF
     QPEERIAQVI QIQSYEDAPY LVLATAQGRV KKSRLSDYES NRSGGLIAIN LNEGDKLIGA
     ALCDNDDDLL LVSEEGQSIR FNANDDQLRP MGRATAGVKG MRFKGDDQLL AMTVVKPDAF
     LLVATSGGYG KRTSLDEYSP QGRGGQGVLT FKYTPKRGKL IAAVVVDEDD EILAITSAGG
     VIRTVVNQIR PSSRATMGVR LVNLEDGVEL LAIDRNVEGE GEEAAEAVAT GAVDGPAERG
     KQTEVDLGID NADEEA
//

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