(data stored in SCRATCH3701 zone)

HOGENOM6: CORK4_1_PE23

ID   CORK4_1_PE23                         STANDARD;      PRT;   866 AA.
AC   CORK4_1_PE23; C4LGC6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (CORK4_1.PE23).
GN   OrderedLocusNames=ckrop_0022;
OS   CORYNEBACTERIUM KROPPENSTEDTII DSM 44385.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=645127;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CORK4_1.PE23.
CC       Corynebacterium kroppenstedtii DSM 44385 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C4LGC6_CORK4
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C4LGC6; -.
DR   EMBL; CP001620; ACR16822.1; -; Genomic_DNA.
DR   RefSeq; YP_002905365.1; NC_012704.1.
DR   STRING; C4LGC6; -.
DR   GeneID; 7876351; -.
DR   GenomeReviews; CP001620_GR; ckrop_0022.
DR   KEGG; ckp:ckrop_0022; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; CORK4_1.PE23; -.
DR   PRODOM; CORK4_1_PE23.
DR   SWISS-2DPAGE; CORK4_1_PE23.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   866 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDDSGNTGG NDLFDRVSPI DIQEEMQSSY IDYAMSVIVG RALPEVRDGM KPVHRRIIYA
     MYDNGYRPER SYVKSARPVA DTMGHFHPHG DSAIYDTLVR MAQPWSMRYP LVDGQGNFGS
     RGNDGPAAMR YTECRLTPLA MEMVRDIREN TVDFEPNYDG KTLEPTILPS RVPNLLMNGS
     GGIAVGMATN IPPHNLTELA QAIFWCLDHY DADEATTLEA VMERVKGPDF PTAGLIVGDK
     GIKDAYTTGR GSIKMRGVTS IEEERGRTII VITELPYQVN PDNLVSSIAE QVRDGKIAGI
     SKIDDESSDR VGMRIVVTLK RDAVPRVVLN NLYKHSQLQT SFGANMLSIV DGVPRTLRLD
     QLLRLYVDHQ IDVIVRRTQH RLDEAEKRAH ILRGLVKALD MLDEVIALIR ASQTPEIART
     GLMDLLDIDE LQADAILRMR LRQLAALERQ KIIDELKELE LTIADLKDIL ARPERQRQIV
     RDELEEIVNN YGDDRRTQII AATGDVTEED LIARENVVAT ITSTGYAKRT KVDLYRNQKR
     GGKGVRGAEL KQDDVVRHFF VTSTHDWILF FTNFGRVYRL KAYELPEASR TARGQHVANL
     LEFQPGEHIA QVIQLQTYED APYLVLATKQ GRVKKSKLTD YDSARSGGLI AINLNEGDSL
     IGAQLCSAND DLLLVSEEGQ AMRFTADDDT LRPMGRATAG VKGMRFRGED ALLALTVVRE
     DSYLMVATSG GYAKRTKMEE YPAKGRGGLG VATFKYNKKR GKLIGALVVD QDDEIFCITT
     DGSVVRSNVK DIRPSSRQTM GVRLVHLDKG SELLAIDRNV EDEGEEHAAK TAEKGNAPTD
     PAEPDPNDPN ADGSDGDGSS DAKDGK
//

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