(data stored in ACNUC7421 zone)

HOGENOM: CORPF_1_PE1011

ID   CORPF_1_PE1011                       STANDARD;      PRT;   501 AA.
AC   CORPF_1_PE1011; D8KMI7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=6-phosphogluconate dehydrogenase, decarboxylating; EC=1.1.1
DE   44; (CORPF_1.PE1011).
GN   Name=gnd; OrderedLocusNames=cpfrc_01011;
OS   CORYNEBACTERIUM PSEUDOTUBERCULOSIS FRC41.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=765874;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CORPF_1.PE1011.
CC       Corynebacterium pseudotuberculosis FRC41 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:D8KMI7_CORPF
CC   -!- FUNCTION: Catalyzes the oxidative decarboxylation of 6-
CC       phosphogluconate to ribulose 5-phosphate and CO(2), with
CC       concomitant reduction of NADP to NADPH (By similarity).
CC   -!- CATALYTIC ACTIVITY: 6-phospho-D-gluconate + NADP(+) = D-ribulose
CC       5-phosphate + CO(2) + NADPH.
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC       ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage):
CC       step 3/3.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase
CC       family.
CC   -!- GENE_FAMILY: HOG000255147 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D8KMI7; -.
DR   EMBL; CP002097; ADK28804.1; -; Genomic_DNA.
DR   RefSeq; YP_003783411.1; NC_014329.1.
DR   ProteinModelPortal; D8KMI7; -.
DR   GeneID; 9448957; -.
DR   GenomeReviews; CP002097_GR; cpfrc_01011.
DR   KEGG; cpu:cpfrc_01011; -.
DR   OMA; LQGQRDF; -.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:EC.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-KW.
DR   InterPro; IPR008927; 6-PGluconate_DH_C-like.
DR   InterPro; IPR006114; 6PGDH_C.
DR   InterPro; IPR006113; 6PGDH_decarbox.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR006184; 6PGdom_BS.
DR   InterPro; IPR013328; DH_multihelical.
DR   InterPro; IPR012284; Fibritin/6PGD_C-extension.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:1.20.5.320; Fibritin/6PGD_C-extension; 1.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:1.10.1040.10; Opine_DH; 1.
DR   Pfam; PF00393; 6PGD; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   PIRSF; PIRSF000109; 6PGD; 1.
DR   SUPFAM; SSF48179; 6DGDH_C_like; 1.
DR   TIGRFAMs; TIGR00873; Gnd; 1.
DR   PROSITE; PS00461; 6PGD; 1.
DR   HOGENOMDNA; CORPF_1.PE1011; -.
KW   6-phosphogluconate dehydrogenase;
KW   Complete proteome; NADP; Oxidoreductase; Pentose shunt.
SQ   SEQUENCE   501 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTLLCPFIAR GVSSGVMTDQ SNLAQIGVVG LAVMGSNLAR NFAHKGHTVA VYNRSAAKTH
     TLMQEHGSEG NFIPSETIEE FVASLEKPRR AIIMVQAGAA TDAVINQLAD AMEPGDIIID
     GGNSLYTDTI RREKEIAARG LNFVGAGISG GEEGALNGPS IMPGGPAESW DALGPLLESI
     SAVVDGTPCV THIGPDGAGH FVKMVHNGIE YADMQVIGEA YQLLRYAAGM EPAEIAEIFK
     TWNKGDLDSY LIEITAEVLS QVDAETGQPL IDVIVDAAGQ KGTGRWTVKA ALDLGIPVTG
     IGEAVFARAL SGAAKQRAAT IGSLPSGTLL TLDKLDTDKE TFVEDVRRAL YASKLVAYAQ
     GFDEIQAGSE EHDWSVDPRD LATIWRGGCI IRAKFLNRIR EAYDADSSLP SLLLDPYFKA
     ELGGLVDSWR RVVVAATQLG LPVPVFTSSL SYYDSLRAER LPAALIQGQR DFFGAHTYKR
     VDKEGTFHTQ WSGDRSEIET S
//

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