(data stored in SCRATCH zone)

HOGENOM: CROTZ_1_PE1004

ID   CROTZ_1_PE1004                       STANDARD;      PRT;   313 AA.
AC   CROTZ_1_PE1004; C9XX89;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Protoheme IX farnesyltransferase; EC=2.5.1 -;AltName:
DE   Full=Heme B farnesyltransferase;AltName: Full=Heme O synthase;
DE   (CROTZ_1.PE1004).
GN   Name=cyoE; OrderedLocusNames=Ctu_10040; ORFNames=CTU_10040;
OS   CRONOBACTER TURICENSIS Z3032.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Cronobacter.
OX   NCBI_TaxID=693216;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CROTZ_1.PE1004.
CC       Cronobacter turicensis z3032, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C9XX89_CROTZ
CC   -!- FUNCTION: Converts heme B (protoheme IX) to heme O by substitution
CC       of the vinyl group on carbon 2 of heme B porphyrin ring with a
CC       hydroxyethyl farnesyl side group (By similarity).
CC   -!- PATHWAY: Porphyrin metabolism; heme O biosynthesis; heme O from
CC       protoheme: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein (By similarity).
CC   -!- MISCELLANEOUS: Carbon 2 of the heme B porphyrin ring is defined
CC       according to the Fischer nomenclature (By similarity).
CC   -!- SIMILARITY: Belongs to the UbiA prenyltransferase family.
CC       Protoheme IX farnesyltransferase subfamily.
CC   -!- GENE_FAMILY: HOG000237290 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C9XX89; -.
DR   EMBL; FN543093; CBA28613.1; -; Genomic_DNA.
DR   RefSeq; YP_003209367.1; NC_013282.2.
DR   STRING; C9XX89; -.
DR   GeneID; 8462087; -.
DR   GenomeReviews; FN543093_GR; Ctu_10040.
DR   KEGG; ctu:Ctu_10040; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008495; F:protoheme IX farnesyltransferase activity; IEA:HAMAP.
DR   GO; GO:0048034; P:heme O biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00154; CyoE_CtaB; 1; -.
DR   InterPro; IPR006369; Protohaem_IX_farnesylTrfase.
DR   InterPro; IPR000537; UbiA_prenyltransferase.
DR   Pfam; PF01040; UbiA; 1.
DR   TIGRFAMs; TIGR01473; CyoE_ctaB; 1.
DR   PROSITE; PS00943; UBIA; 1.
DR   HOGENOMDNA; CROTZ_1.PE1004; -.
KW   protoheme ix farnesyltransferase;
KW   Cell inner membrane; Cell membrane; Complete proteome;
KW   Heme biosynthesis; Membrane; Transferase; Transmembrane;
KW   Transmembrane helix.
SQ   SEQUENCE   313 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDYVEPELQH DGSLRAASMI KQYLQVTKPG IIFGNLISVI GGFLLASKGS IDYPLFLFTL
     VGVSLVVASG CVFNNYIDRD IDRKMERTKN RVLVKGLISP KMSLVYATLL GIAGFMLLWF
     GANPLAMWLA VMGFVVYVGV YSLYMKRHSV YGTLIGSLSG AAPPVIGYCA VTNEFDTGAL
     ILLAIFSLWQ MPHSYAIAIF RFKDYQAANI PVLPVVKGIS VAKNHITLYI IAFAVATLML
     SLGGYAGYKY LVVAAAVSVW WLGMALRGYK AENDKVWARK LFVFSIVAIT SLSVMMSVDF
     MVPDSHNLLT YVW
//

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