(data stored in ACNUC7421 zone)

HOGENOM: CUPNH_1_PE1

ID   CUPNH_1_PE1                          STANDARD;      PRT;   360 AA.
AC   CUPNH_1_PE1; P31892;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Uptake hydrogenase small subunit; EC=1.12.99 6;AltName:
DE   Full=Hydrogenlyase;AltName: Full=Membrane-bound hydrogenase small
DE   subunit;Flags: Precursor; (CUPNH_1.PE1).
GN   Name=hoxK; OrderedLocusNames=PHG001;
OS   RALSTONIA EUTROPHA H16.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=381666;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CUPNH_1.PE1.
CC       Cupriavidus necator megaplasmid pHG1, complete sequence.
CC       1..36860 annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:MBHS_CUPNH
CC   -!- FUNCTION: This enzyme recycles the H(2) produced by nitrogenase to
CC       increase the production of ATP and to protect nitrogenase against
CC       inhibition or damage by O(2) under carbon- or phosphate-limited
CC       conditions.
CC   -!- CATALYTIC ACTIVITY: H(2) + A = AH(2).
CC   -!- COFACTOR: Binds 1 3Fe-4S cluster (By similarity).
CC   -!- COFACTOR: Binds 2 4Fe-4S clusters (By similarity).
CC   -!- SUBUNIT: Heterodimer of a large and a small subunit.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein.
CC   -!- PTM: Predicted to be exported by the Tat system. The position of
CC       the signal peptide cleavage has been experimentally proven.
CC   -!- SIMILARITY: Belongs to the [NiFe]/[NiFeSe] hydrogenase small
CC       subunit family.
CC   -!- GENE_FAMILY: HOG000278822 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P31892; -.
DR   EMBL; M96433; AAA16461.1; -; Unassigned_DNA.
DR   EMBL; AY305378; AAP85757.1; -; Genomic_DNA.
DR   PIR; A43255; A43255.
DR   RefSeq; NP_942643.1; NC_005241.1.
DR   ProteinModelPortal; P31892; -.
DR   STRING; P31892; -.
DR   GeneID; 2656804; -.
DR   GenomeReviews; AY305378_GR; PHG001.
DR   KEGG; reh:PHG001; -.
DR   OMA; MASAGHQ; -.
DR   PhylomeDB; P31892; -.
DR   ProtClustDB; CLSK923788; -.
DR   BioCyc; MetaCyc:HOXKALCA-MON; -.
DR   BioCyc; REUT381666:PHG001-MON; -.
DR   GO; GO:0009375; C:ferredoxin hydrogenase complex; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:InterPro.
DR   GO; GO:0033748; F:hydrogenase (acceptor) activity; IEA:EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   InterPro; IPR006137; NADH_UbQ_OxRdtase-like_20kDa.
DR   InterPro; IPR001821; NiFe_hydrogenase_ssu.
DR   InterPro; IPR006311; TAT_signal.
DR   InterPro; IPR019546; TAT_signal_bac_arc.
DR   Gene3D; G3DSA:3.40.50.700; G3DSA:3.40.50.700; 1.
DR   Pfam; PF01058; Oxidored_q6; 1.
DR   PIRSF; PIRSF000310; NiFe_hyd_ssu; 1.
DR   PRINTS; PR00614; NIHGNASESMLL.
DR   TIGRFAMs; TIGR00391; HydA; 1.
DR   TIGRFAMs; TIGR01409; TAT_signal_seq; 1.
DR   PROSITE; PS51318; TAT; 1.
DR   HOGENOMDNA; CUPNH_1.PE1; -.
KW   membrane-bound [NiFe] hydrogenase small subunit;
KW   3Fe-4S; 4Fe-4S; Cell membrane; Complete proteome;
KW   Direct protein sequencing; Iron; Iron-sulfur; Membrane; Metal-binding;
KW   Oxidoreductase; Plasmid; Signal.
SQ   SEQUENCE   360 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MVETFYEVMR RQGISRRSFL KYCSLTATSL GLGPSFLPQI AHAMETKPRT PVLWLHGLEC
     TCCSESFIRS AHPLAKDVVL SMISLDYDDT LMAAAGHQAE AILEEIMTKY KGNYILAVEG
     NPPLNQDGMS CIIGGRPFIE QLKYVAKDAK AIISWGSCAS WGCVQAAKPN PTQATPVHKV
     ITDKPIIKVP GCPPIAEVMT GVITYMLTFD RIPELDRQGR PKMFYSQRIH DKCYRRPHFD
     AGQFVEEWDD ESARKGFCLY KMGCKGPTTY NACSTTRWNE GTSFPIQSGH GCIGCSEDGF
     WDKGSFYDRL TGISQFGVEA NADKIGGTAS VVVGAAVTAH AAASAIKRAS KKNETSGSEH
//

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