(data stored in SCRATCH3701 zone)

HOGENOM6: CUPPJ_3_PE2557

ID   CUPPJ_3_PE2557                       STANDARD;      PRT;   883 AA.
AC   CUPPJ_3_PE2557; Q46Y44;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (CUPPJ_3.PE2557).
GN   OrderedLocusNames=Reut_A2578;
OS   RALSTONIA EUTROPHA JMP134.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=264198;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS CUPPJ_3.PE2557.
CC       Ralstonia eutropha JMP134 chromosome 1, complete sequence.
CC       1..36860 annotated by Ensembl Genomes
CC   -!- ANNOTATIONS ORIGIN:Q46Y44_CUPPJ
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q46Y44; -.
DR   EMBL; CP000090; AAZ61939.1; -; Genomic_DNA.
DR   RefSeq; YP_296783.1; NC_007347.1.
DR   ProteinModelPortal; Q46Y44; -.
DR   SMR; Q46Y44; 30-528, 542-858.
DR   STRING; Q46Y44; -.
DR   GeneID; 3609602; -.
DR   GenomeReviews; CP000090_GR; Reut_A2578.
DR   KEGG; reu:Reut_A2578; -.
DR   NMPDR; fig|264198.3.peg.3332; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; REUT264198:REUT_A2578-MONOMER; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; CUPPJ_3.PE2557; -.
DR   PRODOM; CUPPJ_3_PE2557.
DR   SWISS-2DPAGE; CUPPJ_3_PE2557.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   883 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDPFAKETLP VSLEEEMRRS YLDYAMSVIV GRALPDVRDG LKPVHRRVLY AMHELNNDWN
     RAYKKSARIV GDVIGKYHPH GDTAVYDTIV RMAQNFSLRY MLVDGQGNFG SVDGDNAAAM
     RYTEIRLSKI AHEMLHDIDK ETVDFDPNYD GSEKEPAILP ARIPNLLING SSGIAVGMAT
     NIPPHNLNEI VDGCLHLLRN PQATVDELIE LIPAPDFPTA GIIYGIQGVR EGYRTGRGRV
     VMRARTHFED IDRGQRQAII VDELPYQVNK RTLLERIAEL VTEKKVEGIS DIRDESDKSG
     MRVVIELKRN EVPEVVLNNL YKNTQLQDTF GMNMVALVDR QPRLLNLKQM LEYFLQHRRE
     VVTRRTVFEL RKARERGHVL EGLAVALANI DEFIAIIKAA PTPPIAKQEL MAKSWDSGLV
     REMLARAEAD TPGGRASYRP DGLPAMFGMQ GDGLYRLSDS QAQEILQMRL QRLTGLEQDK
     IVQEYRDVMA IIADLLDILA RPERITTIIS DELTAIRAEF GDERRSQIEL NATELDTEDL
     ITPQDMVVTL SHSGYMKSQP ISEYRAQKRG GRGKLATATK EDDWIDTLFV ANTHDYILCF
     SNRGRLYWLK VYEVPQGSRN SRGRPIVNMF PLSDGEKINV ILPVRQFDAE HFIFMATARG
     TVKKTALTEF SNPRKAGIIA VDLDEGDYLI GAAVTDGQHD VMLFSDAGKA VRFDENDVRP
     MGRQARGVRG MNLDESQTVI AMLVAPAETA EQTEAGSPGS VLTATENGYG KRTPIAEYTR
     HGRGTKGMIA IQTSERNGRV VAAALVSPDD EIMLITTGGV LIRTRVAEIR EMGRATQGVT
     LINVDEGTKL SGLQRIVETD ADNGAGSEEA EEADGAADAD ANS
//

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