(data stored in ACNUC1944 zone)

HOGENOM: DANRE10_10_PE11

ID   DANRE10_10_PE11                      STANDARD;      PRT;   475 AA.
AC   DANRE10_10_PE11; Q6DBW1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Ras-GEF domain-containing family member 1B-B;
DE   (DANRE10_10.PE11).
GN   Name=rasgef1bb; Synonyms=rasgef; ORFNames=zgc:91814;
OS   DANIO RERIO.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Actinopterygii; Actinopteri; Neopterygii; Teleostei; Elopocephala;
OC   Clupeocephala; Otocephala; Ostariophysi; Otophysi; Cypriniphysi;
OC   Cypriniformes; Cyprinoidea; Cyprinidae; Danio.
OX   NCBI_TaxID=7955;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS DANRE10_10.PE11.
CC       Danio rerio chromosome 10 Zv9 partial sequence 8820539..9801566 annotat
CC       by Ensembl
CC   -!- ANNOTATIONS ORIGIN:RG1BB_DANRE
CC   -!- FUNCTION: Guanine nucleotide exchange factor (GEF) for Ras family
CC       proteins (By similarity).
CC   -!- DEVELOPMENTAL STAGE: Expressed throughout embryogenesis from the
CC       blastula sphere stage (4 hours post fertilization).
CC   -!- SIMILARITY: Contains 1 N-terminal Ras-GEF domain.
CC   -!- SIMILARITY: Contains 1 Ras-GEF domain.
CC   -!- GENE_FAMILY: HOG000018026 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Danio_rerio;ENSDARG00000044251;ENSDART00000064968;ENSDARP00000064967.
DR   EMBL; BC078340; - ;
DR   UniProtKB/Swiss-Prot; Q6DBW1; -.
DR   EMBL; BC078340; AAH78340.1; -; mRNA.
DR   IPI; IPI00492509; -.
DR   RefSeq; NP_001003479.1; NM_001003479.1.
DR   UniGene; Dr.13285; -.
DR   ProteinModelPortal; Q6DBW1; -.
DR   Ensembl; ENSDART00000064968; ENSDARP00000064967; ENSDARG00000044251.
DR   GeneID; 445085; -.
DR   KEGG; dre:445085; -.
DR   CTD; 445085; -.
DR   ZFIN; ZDB-GENE-040801-220; rasgef1bb.
DR   eggNOG; fiNOG15286; -.
DR   GeneTree; ENSGT00560000076949; -.
DR   InParanoid; Q6DBW1; -.
DR   OMA; QECFNIG; -.
DR   OrthoDB; EOG4B5P54; -.
DR   ArrayExpress; Q6DBW1; -.
DR   Bgee; Q6DBW1; -.
DR   GO; GO:0005622; C:intracellular; IEA:InterPro.
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR   InterPro; IPR019804; Ras_G-nucl-exch_fac_CS.
DR   InterPro; IPR008937; Ras_GEF.
DR   InterPro; IPR023578; Ras_GEF_dom.
DR   InterPro; IPR001895; RasGRF_CDC25.
DR   Gene3D; G3DSA:1.10.840.10; RasGRF_CDC25; 1.
DR   PANTHER; PTHR23113; Ras_GEF; 1.
DR   Pfam; PF00617; RasGEF; 1.
DR   Pfam; PF00618; RasGEF_N; 1.
DR   SMART; SM00147; RasGEF; 1.
DR   SUPFAM; SSF48366; Ras_GEF; 1.
DR   PROSITE; PS00720; RASGEF; 1.
DR   PROSITE; PS50009; RASGEF_CAT; 1.
DR   PROSITE; PS50212; RASGEF_NTER; 1.
DR   HOGENOMDNA; DANRE10_10.PE11; -.
KW   ENSDARG000000442515old_1320000031; ENSDARP000000649671old_1320000031;
KW   BC078340;
KW   Complete proteome; Guanine-nucleotide releasing factor;
KW   Reference proteome.
SQ   SEQUENCE   475 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPQTTPYSSK FNPSAYSSSH SHRQPVEENY GGLHYRDNKL VSGSLEALIQ LLVPTVDYYP
     DRSYIFTFLL SSRLFLNPFE LMSRVCYLGV DHHRVGDPQM DKKRIRDIAP KIVQLLTEWT
     ETFPYDFRDE RMMRSLKEMT HRLAFGDELS RRAMQRLIQR LLRKLTTLGQ YEESLATTSA
     AAAIDRPVAL KSKQQLVRRD DCVLNLCDDP FIFAQQLTHI EMERLSYIGP EEFVRAFAQK
     RPSDNHKSFF SKRKASNLEA YVEWFNRLSY LTATEICMPV KKKHRARVLE FFIDVAQECF
     NIGNFNSLMA IITGMNMNPV SRLKKTWGKV NTDKFDILVH QMDPSSNFYS YRTALRGATQ
     RSSTAHTSQE MIVIPFFSLF IKDIYFLNEG CANRLSNGHI NFEKFWELAK QVSEFLSWRQ
     VICPFERDRK TLQYLISAPV FSEDELQLAS YESEGPENNL ERDTRRSLRS SLSRM
//

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