(data stored in ACNUC7421 zone)

HOGENOM: DANRE1_58_PE22

ID   DANRE1_58_PE22                       STANDARD;      PRT;   353 AA.
AC   DANRE1_58_PE22; A9JRE2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylthioribose-1-phosphate isomerase; Short=M1Pi;
DE   Short=MTR-1-P isomerase; EC=5.3.1 23;AltName:
DE   Full=S-methyl-5-thioribose-1-phosphate isomerase;AltName:
DE   Full=Translation initiation factor eIF-2B subunit alpha/beta/delta-like
DE   protein; (DANRE1_58.PE22).
GN   Name=mri1; ORFNames=zgc:172216;
OS   DANIO RERIO.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Actinopterygii; Actinopteri; Neopterygii; Teleostei; Elopocephala;
OC   Clupeocephala; Otocephala; Ostariophysi; Otophysi; Cypriniphysi;
OC   Cypriniformes; Cyprinoidea; Cyprinidae; Danio.
OX   NCBI_TaxID=7955;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS DANRE1_58.PE22.
CC       Danio rerio chromosome 1 Zv9 partial sequence 55396904..56396189 annota
CC       by Ensembl
CC   -!- ANNOTATIONS ORIGIN:MTNA_DANRE
CC   -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1-
CC       phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-methyl-5-thio-alpha-D-ribose 1-phosphate =
CC       S-methyl-5-thio-D-ribulose 1-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via
CC       salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose
CC       1-phosphate: step 1/6.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family. MtnA subfamily.
CC   -!- GENE_FAMILY: HOG000224730 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Danio_rerio;ENSDARG00000075754;ENSDART00000111671;ENSDARP00000098757.
DR   EMBL; BC155626; - ;
DR   EMBL; BC171374; - ;
DR   EMBL; BC171376; - ;
DR   EMBL; CU467849; - ;
DR   UniProtKB/Swiss-Prot; A9JRE2; -.
DR   EMBL; BC155626; AAI55627.1; -; mRNA.
DR   EMBL; BC171374; AAI71374.1; -; mRNA.
DR   EMBL; BC171376; AAI71376.1; -; mRNA.
DR   IPI; IPI00882847; -.
DR   RefSeq; NP_001104708.1; NM_001111238.1.
DR   UniGene; Dr.85012; -.
DR   ProteinModelPortal; A9JRE2; -.
DR   STRING; A9JRE2; -.
DR   Ensembl; ENSDART00000111671; ENSDARP00000098757; ENSDARG00000075754.
DR   GeneID; 100002302; -.
DR   KEGG; dre:100002302; -.
DR   ZFIN; ZDB-GENE-080204-109; zgc:172216.
DR   OMA; EDGWKVI; -.
DR   OrthoDB; EOG41C6WN; -.
DR   Bgee; A9JRE2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR005251; IF-2BI_MTNA.
DR   InterPro; IPR011559; Initiation_fac_2B_a/b/d.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   TIGRFAMs; TIGR00524; EIF-2B_rel; 1.
DR   TIGRFAMs; TIGR00512; Salvage_mtnA; 1.
DR   HOGENOMDNA; DANRE1_58.PE22; -.
KW   ENSDARG000000757545old_1320000031; ENSDARP000000987571old_1320000031;
KW   B8JLC4_DANRE; BC155626; BC171374; BC171376; CU467849;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase;
KW   Methionine biosynthesis; Nucleus; Reference proteome.
SQ   SEQUENCE   353 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTLEAIRYRS GSLQILNQLL LPRETVYDEI RSVRDGYEAI KSMKVRGAPA IAIVGCLSLA
     VELRAGAGAE DLVSFVRDSL CHLTSARPTA VNMGRAAREL MEFTENESME KNTEQLRDSV
     IGWIEEMLER DVNDNKKIGN YGAQHILSGV PRDSVTILTH CNTGSLATAG YGTALGVVRS
     LHMLGRLKRL YCTETRPYNQ GARLTAYEAV AEGFPATLIT DSMAALAMRE KSITAVVVGA
     DRVVANGDTA NKVGTYQLAI AAKHHGIPFY VAAPSTSCDL SLESGRDIVI EERPAEELTS
     INGVPVAAPG IDVWNPAFDV TPHQLITGGI ITELGVFLPS ELQAALTGRL TAL
//

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