(data stored in ACNUC19913 zone)

HOGENOM: DANRE2_6_PE10

ID   DANRE2_6_PE10                        STANDARD;      PRT;   434 AA.
AC   DANRE2_6_PE10; Q7T3B6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Protein C (DANRE2_6.PE10) (Inactivator of coagulation
DE   factors Va and VIIIa); .
GN   Name=proc; ORFNames=zgc:63987;
OS   DANIO RERIO.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Actinopterygii; Actinopteri; Neopterygii; Teleostei; Elopocephala;
OC   Clupeocephala; Otocephala; Ostariophysi; Otophysi; Cypriniphysi;
OC   Cypriniformes; Cyprinoidea; Cyprinidae; Danio.
OX   NCBI_TaxID=7955;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS DANRE2_6.PE10.
CC       Danio rerio chromosome 2 Zv9 partial sequence 4966127..5963999 annotate
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:Q7T3B6_DANRE
CC   -!- SIMILARITY: Belongs to the peptidase S1 family.
CC   -!- SIMILARITY: Contains 1 Gla (gamma-carboxy-glutamate) domain.
CC   -!- SIMILARITY: Contains 1 peptidase S1 domain.
CC   -!- GENE_FAMILY: HOG000251821 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Danio_rerio;ENSDARG00000038258;ENSDART00000081506;ENSDARP00000075947.
DR   EMBL; BC053182; - ;
DR   EMBL; CU467941; - ;
DR   UniProtKB/Swiss-Prot; Q7T3B6; -.
DR   EMBL; BC053182; AAH53182.1; -; mRNA.
DR   IPI; IPI00972771; -.
DR   RefSeq; NP_956650.1; NM_200356.1.
DR   UniGene; Dr.131057; -.
DR   UniGene; Dr.85899; -.
DR   HSSP; P00746; 1FDP.
DR   ProteinModelPortal; Q7T3B6; -.
DR   SMR; Q7T3B6; 41-85.
DR   STRING; Q7T3B6; -.
DR   MEROPS; S01.218; -.
DR   GeneID; 393327; -.
DR   KEGG; dre:393327; -.
DR   CTD; 5624; -.
DR   ZFIN; ZDB-GENE-060824-5; proc.
DR   eggNOG; fiNOG09254; -.
DR   GeneTree; ENSGT00560000076714; -.
DR   ArrayExpress; Q7T3B6; -.
DR   Bgee; Q7T3B6; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   InterPro; IPR017857; Coagulation_fac_subgr_Gla_dom.
DR   InterPro; IPR006209; EGF.
DR   InterPro; IPR006210; EGF-like.
DR   InterPro; IPR013032; EGF-like_reg_CS.
DR   InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR   InterPro; IPR000742; EGF_3.
DR   InterPro; IPR018097; EGF_Ca-bd_CS.
DR   InterPro; IPR000294; GLA_domain.
DR   InterPro; IPR009003; Pept_cys/ser_Trypsin-like.
DR   InterPro; IPR012224; Pept_S1A_FX.
DR   InterPro; IPR018114; Peptidase_S1/S6_AS.
DR   InterPro; IPR001254; Peptidase_S1_S6.
DR   InterPro; IPR001314; Peptidase_S1A.
DR   Gene3D; G3DSA:4.10.740.10; Coagulation_factor_Gla; 1.
DR   Pfam; PF00008; EGF; 1.
DR   Pfam; PF00594; Gla; 1.
DR   Pfam; PF00089; Trypsin; 1.
DR   PIRSF; PIRSF001143; Factor_X; 1.
DR   PRINTS; PR00722; CHYMOTRYPSIN.
DR   PRINTS; PR00001; GLABLOOD.
DR   SMART; SM00181; EGF; 2.
DR   SMART; SM00069; GLA; 1.
DR   SMART; SM00020; Tryp_SPc; 1.
DR   SUPFAM; SSF50494; Pept_Ser_Cys; 1.
DR   SUPFAM; SSF57630; VitK_dep_GLA; 1.
DR   PROSITE; PS00010; ASX_HYDROXYL; 1.
DR   PROSITE; PS00022; EGF_1; 1.
DR   PROSITE; PS01186; EGF_2; 2.
DR   PROSITE; PS50026; EGF_3; 1.
DR   PROSITE; PS01187; EGF_CA; 1.
DR   PROSITE; PS00011; GLA_1; 1.
DR   PROSITE; PS50998; GLA_2; 1.
DR   PROSITE; PS50240; TRYPSIN_DOM; 1.
DR   PROSITE; PS00134; TRYPSIN_HIS; 1.
DR   PROSITE; PS00135; TRYPSIN_SER; 1.
DR   HOGENOMDNA; DANRE2_6.PE10; -.
KW   ENSDARG000000382585old_1320000031; ENSDARP000000759471old_1320000031;
KW   Q7T3B6_DANRE; BC053182; CU467941;
KW   Calcium; EGF-like domain; Hydrolase; Protease; Serine protease.
SQ   SEQUENCE   434 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRSLFFCALT LVVFCSDGAL CKSVFSSSPN AHMLLRSRRA NTFMEELKPA SLERECREEL
     CDFEEAREIF ITREATLEFW TAYKDGNQCT TNPCVHGKCV DLLQDFSCTC DSGFEGKHCD
     LRRTATNCSL NNGDCDHDCH ESKDGLARTC SCIKGYQLQD NSRKCTPKND ASCGQIRIPK
     SAYANKPKPV LQPWVMGGNV GKRGESPWQA LILNHLGRFH CGGVLIDENW VLTAAHCLET
     SSKFSVRLGD YQRFRFEGSE VTLPVKQHIS HPQYNPITVD NDIALLRLEG PVKFSTYILP
     ACLPSLELAK RMLHRNGTVT VITGWGKNNQ SATSYNSTLH YVELPIVDNK ECSRHMMNNL
     SDNMLCAGVL GQVKDACEGD SGGPMMTLFH DTWFLVGLVS WGEGCGQRDK LGIYTKVASY
     LDWIDSVRQG WDKV
//

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