(data stored in ACNUC7421 zone)

HOGENOM: DEHSB_1_PE1002

ID   DEHSB_1_PE1002                       STANDARD;      PRT;   189 AA.
AC   DEHSB_1_PE1002; A5FQD3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=GTP cyclohydrolase 1; EC=3.5.4 16;AltName: Full=GTP
DE   cyclohydrolase I; Short=GTP-CH-I; (DEHSB_1.PE1002).
GN   Name=folE; OrderedLocusNames=DehaBAV1_1014;
OS   DEHALOCOCCOIDES SP. BAV1.
OC   Bacteria; Chloroflexi; Dehalococcoidetes; Dehalococcoides.
OX   NCBI_TaxID=216389;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS DEHSB_1.PE1002.
CC       Dehalococcoides sp. BAV1, complete genome.
CC       / IFO 0083) chromosome G, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:GCH1_DEHSB
CC   -!- CATALYTIC ACTIVITY: GTP + H(2)O = formate + 2-amino-4-hydroxy-6-
CC       (erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.
CC   -!- PATHWAY: Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate
CC       biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step
CC       1/1.
CC   -!- SUBUNIT: Homopolymer (By similarity).
CC   -!- SIMILARITY: Belongs to the GTP cyclohydrolase I family.
CC   -!- GENE_FAMILY: HOG000221222 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A5FQD3; -.
DR   EMBL; CP000688; ABQ17594.1; -; Genomic_DNA.
DR   RefSeq; YP_001214472.1; NC_009455.1.
DR   ProteinModelPortal; A5FQD3; -.
DR   STRING; A5FQD3; -.
DR   GeneID; 5131389; -.
DR   GenomeReviews; CP000688_GR; DehaBAV1_1014.
DR   KEGG; deb:DehaBAV1_1014; -.
DR   eggNOG; COG0302; -.
DR   OMA; KQIATAM; -.
DR   ProtClustDB; PRK09347; -.
DR   BioCyc; DSP216389:DEHABAV1_1014-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003934; F:GTP cyclohydrolase I activity; IEA:EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00223; FolE; 1; -.
DR   InterPro; IPR001474; GTP_CycHdrlase_I.
DR   InterPro; IPR020602; GTP_CycHdrlase_I/CN_OxRdtase.
DR   InterPro; IPR018234; GTP_CycHdrlase_I_CS.
DR   Pfam; PF01227; GTP_cyclohydroI; 1.
DR   TIGRFAMs; TIGR00063; FolE; 1.
DR   PROSITE; PS00859; GTP_CYCLOHYDROL_1_1; 1.
DR   PROSITE; PS00860; GTP_CYCLOHYDROL_1_2; FALSE_NEG.
DR   HOGENOMDNA; DEHSB_1.PE1002; -.
KW   Complete proteome; GTP-binding; Hydrolase; Metal-binding;
KW   Nucleotide-binding; One-carbon metabolism; Zinc.
SQ   SEQUENCE   189 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MFDEQAIKQS VQNILVAIGE DPDREGLKET PRRVAQMYTE LFSGMNQDPA EVLRVGYELG
     HREMVIIKDI PFYSMCEHHL LPFSGVVHIG YIPNIDGRVV GISKLARVVE IYAKRPQIQE
     RMATQIADAI MDGLKCDGVA VVIEAEHMCM VMRGIKKPGS RVITSALRGS FHKSPAARAE
     FLSLIQHKG
//

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