(data stored in ACNUC7421 zone)

HOGENOM: DEIDV_1_PE1000

ID   DEIDV_1_PE1000                       STANDARD;      PRT;   210 AA.
AC   DEIDV_1_PE1000; C1D1S2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Putative Imidazole glycerol phosphate synthase subunit hisH
DE   (DEIDV_1.PE1000) (IGP synthase glutamine amidotransferase subunit) (IGP
DE   synthase subunit hisH) (ImGP synthase subunit hisH) (IGPS subunit hisH); .
GN   OrderedLocusNames=Deide_09190;
OS   DEINOCOCCUS DESERTI VCD115.
OC   Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=546414;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS DEIDV_1.PE1000.
CC       Deinococcus deserti VCD115 chromosome, complete genome.
CC       / IFO 0083) chromosome G, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:C1D1S2_DEIDV
CC   -!- FUNCTION: IGPS catalyzes the conversion of PRFAR and glutamine to
CC       IGP, AICAR and glutamate. The hisH subunit provides the glutamine
CC       amidotransferase activity that produces the ammonia necessary to
CC       hisF for the synthesis of IGP and AICAR (By similarity).
CC   -!- CATALYTIC ACTIVITY: 5-[(5-phospho-1-deoxyribulos-1-
CC       ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-
CC       carboxamide + L-glutamine = imidazole-glycerol phosphate + 5-
CC       aminoimidazol-4-carboxamide ribonucleotide + L-glutamate + H(2)O.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-histidine biosynthesis; L-
CC       histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.
CC   -!- SUBUNIT: Heterodimer of hisH and hisF (By similarity).
CC   -!- SIMILARITY: Contains 1 glutamine amidotransferase type-1 domain.
CC   -!- GENE_FAMILY: HOG000025030 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C1D1S2; -.
DR   EMBL; CP001114; ACO45796.1; -; Genomic_DNA.
DR   RefSeq; YP_002785550.1; NC_012526.1.
DR   ProteinModelPortal; C1D1S2; -.
DR   STRING; C1D1S2; -.
DR   GeneID; 7739364; -.
DR   GenomeReviews; CP001114_GR; Deide_09190.
DR   KEGG; ddr:Deide_09190; -.
DR   OMA; VCVLKEV; -.
DR   ProtClustDB; PRK13181; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0000107; F:imidazoleglycerol-phosphate synthase activity; IEA:HAMAP.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0000105; P:histidine biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00278; HisH; 1; -.
DR   InterPro; IPR017926; GATASE_1.
DR   InterPro; IPR010139; Imidazole-glycPsynth_HisH.
DR   Pfam; PF00117; GATase; 1.
DR   PIRSF; PIRSF000495; Amidotransf_hisH; 1.
DR   TIGRFAMs; TIGR01855; IMP_synth_hisH; 1.
DR   PROSITE; PS51273; GATASE_TYPE_1; 1.
DR   HOGENOMDNA; DEIDV_1.PE1000; -.
KW   Amino-acid biosynthesis; Complete proteome;
KW   Glutamine amidotransferase; Histidine biosynthesis; Transferase.
SQ   SEQUENCE   210 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTPRCEVLLL DYGGGNVRSA AKALERAGME VRVSADPADV PHAPAVVVPG QGHFRQVMEA
     FDSSGFHAPV MQAAQAGTPL LGICVGMQML LTESEEAPGV QGLNLVPGVV RRFEAVPERK
     VPQMGWNSLD KVGDSPLLRD LTCPAYAYFV HSYYVPLEVE VDAGAISEYG VPFWSAFSQG
     NIHATQFHPE KSGAVGLAIL ERFRRHVLGH
//

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