(data stored in ACNUC7421 zone)

HOGENOM: DELAS_1_PE1001

ID   DELAS_1_PE1001                       STANDARD;      PRT;   318 AA.
AC   DELAS_1_PE1001; A9BRT1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=HPr kinase/phosphorylase; Short=HPrK/P; EC=2.7.11.-;
DE   EC=2.7.4 -;AltName: Full=HPr(Ser) kinase/phosphorylase; (DELAS_1.PE1001).
GN   Name=hprK; OrderedLocusNames=Daci_1002;
OS   DELFTIA ACIDOVORANS SPH-1.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Delftia.
OX   NCBI_TaxID=398578;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS DELAS_1.PE1001.
CC       Delftia acidovorans SPH-1 chromosome, complete genome.
CC       / IFO 0083) chromosome G, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:HPRK_DELAS
CC   -!- FUNCTION: Catalyzes the ATP- as well as the pyrophosphate-
CC       dependent phosphorylation of a specific serine residue in HPr, a
CC       phosphocarrier protein of the phosphoenolpyruvate-dependent sugar
CC       phosphotransferase system (PTS). HprK/P also catalyzes the
CC       pyrophosphate-producing, inorganic phosphate-dependent
CC       dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-
CC       Ser-HPr) (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + HPr = ADP + P-Ser-HPr.
CC   -!- CATALYTIC ACTIVITY: P-Ser-HPr + phosphate = HPr + diphosphate.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- SUBUNIT: Homohexamer (By similarity).
CC   -!- DOMAIN: The Walker A ATP-binding motif also binds Pi and PPi (By
CC       similarity).
CC   -!- MISCELLANEOUS: Both phosphorylation and phosphorolysis are carried
CC       out by the same active site and suggest a common mechanism for
CC       both reactions (By similarity).
CC   -!- SIMILARITY: Belongs to the HPrK/P family.
CC   -!- GENE_FAMILY: HOG000099173 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A9BRT1; -.
DR   EMBL; CP000884; ABX33648.1; -; Genomic_DNA.
DR   RefSeq; YP_001562033.1; NC_010002.1.
DR   ProteinModelPortal; A9BRT1; -.
DR   STRING; A9BRT1; -.
DR   GeneID; 5746556; -.
DR   GenomeReviews; CP000884_GR; Daci_1002.
DR   KEGG; dac:Daci_1002; -.
DR   OMA; GIGKSEC; -.
DR   ProtClustDB; PRK05428; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:two-component sensor activity; IEA:InterPro.
DR   GO; GO:0006109; P:regulation of carbohydrate metabolic process; IEA:InterPro.
DR   HAMAP; MF_01249; HPr_kinase; 1; -.
DR   InterPro; IPR003755; Sig_transdc_Ser_kin/Pase_Hpr.
DR   InterPro; IPR011104; Sig_transdc_Ser_kin/Pase_Hpr_C.
DR   InterPro; IPR011126; Sig_transdc_Ser_kin/Pase_Hpr_N.
DR   Pfam; PF07475; Hpr_kinase_C; 1.
DR   Pfam; PF02603; Hpr_kinase_N; 1.
DR   HOGENOMDNA; DELAS_1.PE1001; -.
KW   HPr kinase/phosphorylase;
KW   ATP-binding; Complete proteome; Kinase; Magnesium; Metal-binding;
KW   Multifunctional enzyme; Nucleotide-binding;
KW   Serine/threonine-protein kinase; Transferase.
SQ   SEQUENCE   318 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRPSAISADV LFEEFRSSLR WEWVAGLGAS ERRFDEMAVR SARSGADLVG YLNYIHPYRL
     QVLGEREIAY LSNATPQDCQ RRVARIVTLE PPVLVLADGQ TAPEALLSMC ERAHIPMFST
     REQSAFVIDV LRAYLAKHFA DRTTMHGVFM DILGMGVLIT GESGLGKSEL GLELVTRGNG
     LVADDAVDLY RINQTTIEGK CPELLQNLLE VRGIGLLDIR AIFGETAVRR KMRLKLIVHL
     VRKETMEREY ERLPAEPLTQ DVLGVPVRKV VIQVVAGRNI AVLVEAAVRN AILQLRGIDT
     YQEFVQRHRR AMERGDTF
//

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