(data stored in ACNUC10043 zone)

HOGENOM: DEMUC1_1_PE1003

ID   DEMUC1_1_PE1003                      STANDARD;      PRT;   224 AA.
AC   DEMUC1_1_PE1003; E8R9Z6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Endonuclease V; EC=3.1.21 7;AltName: Full=Deoxyinosine
DE   3'endonuclease;AltName: Full=Deoxyribonuclease V; (DEMUC1_1.PE1003).
GN   Name=nfi; OrderedLocusNames=Desmu_1020;
OS   DESULFUROCOCCUS MUCOSUS DSM 2162.
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Desulfurococcus.
OX   NCBI_TaxID=765177;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS DEMUC1_1.PE1003.
CC       Desulfurococcus mucosus DSM 2162 chromosome, complete genome.
CC       / IFO 0083) chromosome G, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E8R9Z6_DESM0
CC   -!- FUNCTION: Selectively cleaves double-stranded DNA at the second
CC       phosphodiester bond 3' to a deoxyinosine leaving behind the intact
CC       lesion on the nicked DNA. Acts in DNA repair (By similarity).
CC   -!- CATALYTIC ACTIVITY: Endonucleolytic cleavage at apurinic or
CC       apyrimidinic sites to products with a 5'-phosphate.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the endonuclease V family.
CC   -!- GENE_FAMILY: HOG000229135 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E8R9Z6; -.
DR   EMBL; CP002363; ADV65322.1; -; Genomic_DNA.
DR   RefSeq; YP_004176804.1; NC_014961.1.
DR   GeneID; 10153724; -.
DR   GenomeReviews; CP002363_GR; Desmu_1020.
DR   KEGG; dmu:Desmu_1020; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043737; F:deoxyribonuclease V activity; IEA:HAMAP.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0006281; P:DNA repair; IEA:HAMAP.
DR   HAMAP; MF_00801; Endonuclease_5; 1; -.
DR   InterPro; IPR007581; Endonuclease-V.
DR   Pfam; PF04493; Endonuclease_5; 1.
DR   HOGENOMDNA; DEMUC1_1.PE1003; -.
KW   endonuclease V;
KW   Complete proteome; Cytoplasm; DNA damage; DNA repair; Endonuclease;
KW   Hydrolase; Magnesium; Metal-binding; Nuclease.
SQ   SEQUENCE   224 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSLFDYRRAV RLQEALSRRV LEEAASFPGL DPSRVRLVAG VDAAYGGGVQ AGCAVLVDYA
     SSTQLAYTCH VREPPIPYVP GLLAFREAPV YIKALRKLPE NPDIILVDGH GLTHPRALGI
     ATHIGLVLGK PTIGVAKNPL YGEEKTVNGR RLITAHGVTA GEILEPVKGV KLYVSIGYLI
     RLEDAVTVVK HLMKPGLKLP LPLHLADKYS KNTARQGYIA SKKK
//

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