(data stored in SCRATCH3701 zone)

HOGENOM6: DESAH_1_PE3593

ID   DESAH_1_PE3593                       STANDARD;      PRT;   870 AA.
AC   DESAH_1_PE3593; C0QA00;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=GyrA; EC=5.99.1 3; (DESAH_1.PE3593).
GN   Name=gyrA; OrderedLocusNames=HRM2_36590;
OS   DESULFOBACTERIUM AUTOTROPHICUM HRM2.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfobacterales;
OC   Desulfobacteraceae; Desulfobacterium.
OX   NCBI_TaxID=177437;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS DESAH_1.PE3593.
CC       Desulfobacterium autotrophicum HRM2, complete genome.
CC       / IFO 0083) chromosome G, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:C0QA00_DESAH
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C0QA00; -.
DR   EMBL; CP001087; ACN16718.1; -; Genomic_DNA.
DR   RefSeq; YP_002604882.1; NC_012108.1.
DR   STRING; C0QA00; -.
DR   GeneID; 7502558; -.
DR   GenomeReviews; CP001087_GR; HRM2_36590.
DR   KEGG; dat:HRM2_36590; -.
DR   OMA; TGRGRIY; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; DESAH_1.PE3593; -.
DR   PRODOM; DESAH_1_PE3593.
DR   SWISS-2DPAGE; DESAH_1_PE3593.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   870 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLNQEEITNT ISIETEMKKS YLEYAMSVII GRALPDVRDG LKPVHRRVLF AMRELRNDWN
     KPYKKSARIV GDVIGKYHPH GDTAVYDTMV RMAQDFSLRY TLVDGQGNFG SVDGDSPAAM
     RYTEVRMKKI AHQMLADLEK ETVDFIPNYD ETMAEPSVLP TKFPALLVNG SSGIAVGMTT
     NIPPHNIGEV VQGLIALLEK PDITIEELMI HIPGPDFPTY GKIYGRKGIH EAYTTGRGII
     TVRAKVEVEV NSKTKAETIV VTELPYQVNK AKLVEKIAEL MRAKVIEGAS YVRDESDRQG
     MRIAIGLKRD QFPDVVINQL YKHTNMHTSF GIIFLAVVNN RPELFTLKEL LEQFLNHRRS
     VIIRRTLFDQ KKAMDRAHIL EGLIKALDNL DAVVALIRAS QSPEEAKAGL VQSFELTQIQ
     AQAILEMRLQ RLTGLERDKI NEEYAQLLKD LAWYQEILSS DQVVRDIIKQ ELTELKDEYQ
     DDRRTQIVEA TGEINIEDLI AEEDMVVTVT RSGYIKRNPI TLYASQHRGG KGKTAMGTKD
     EDFVEHLFVA STHHTFLFIT NLGKVYQSKV YELPMAGRTS LGKAIVNLLN FEQGEKLATV
     LTVPEFVEDR YVVMATKLGR VKKTDLMAYS RPRSGGLIGI KLADDDELIA AGITDGKTDI
     FLGSEGGKVI RFDENDVRTT ARGSMGVRGM RIDPGSCVVG MEVLNHGQTL LTVTENGYGK
     RTLIQEYRSQ TRGGKGVFSI RTSERNGKMV ALLLVEDEDE LMLVTDGGKL IRTGIQDISV
     ISRNTQGVKL INLSPGEKLI GAARLPEEEE EEKDESEASE QSEEGRVDPH EGPDEFDAGE
     SHEPDSTESE DDKPDDSGSW KDESEDDESE
//

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