(data stored in ACNUC7421 zone)

HOGENOM: DESDG_1_PE1008

ID   DESDG_1_PE1008                       STANDARD;      PRT;   298 AA.
AC   DESDG_1_PE1008; Q313T8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Phosphoribosylaminoimidazole-succinocarboxamide synthase;
DE   EC=6.3.2 6;AltName: Full=SAICAR synthetase; (DESDG_1.PE1008).
GN   Name=purC; OrderedLocusNames=Dde_1007;
OS   DESULFOVIBRIO ALASKENSIS G20.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Desulfovibrio.
OX   NCBI_TaxID=207559;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS DESDG_1.PE1008.
CC       Desulfovibrio desulfuricans subsp. desulfuricans str. G20 chromosome,
CC       complete genome.
CC   -!- ANNOTATIONS ORIGIN:Q313T8_DESDG
CC   -!- CATALYTIC ACTIVITY: ATP + 5-amino-1-(5-phospho-D-
CC       ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate +
CC       (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-
CC       carboxamido)succinate.
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway;
CC       5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-
CC       amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.
CC   -!- SIMILARITY: Belongs to the SAICAR synthetase family.
CC   -!- GENE_FAMILY: HOG000230360 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q313T8; -.
DR   EMBL; CP000112; ABB37808.1; -; Genomic_DNA.
DR   RefSeq; YP_387503.1; NC_007519.1.
DR   ProteinModelPortal; Q313T8; -.
DR   STRING; Q313T8; -.
DR   GeneID; 3755509; -.
DR   GenomeReviews; CP000112_GR; Dde_1007.
DR   KEGG; dde:Dde_1007; -.
DR   NMPDR; fig|207559.3.peg.26; -.
DR   eggNOG; COG0152; -.
DR   OMA; LTLMDEV; -.
DR   ProtClustDB; PRK13961; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004639; F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; IEA:HAMAP.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00137; SAICAR_synth; 1; -.
DR   InterPro; IPR013816; ATP_grasp_subdomain_2.
DR   InterPro; IPR001636; SAICAR_synth.
DR   InterPro; IPR018236; SAICAR_synthetase_CS.
DR   Gene3D; G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
DR   PANTHER; PTHR11609; SAICAR_synt; 1.
DR   Pfam; PF01259; SAICAR_synt; 1.
DR   TIGRFAMs; TIGR00081; PurC; 1.
DR   PROSITE; PS01057; SAICAR_SYNTHETASE_1; 1.
DR   PROSITE; PS01058; SAICAR_SYNTHETASE_2; 1.
DR   HOGENOMDNA; DESDG_1.PE1008; -.
KW   ATP-binding; Complete proteome; Ligase; Nucleotide-binding;
KW   Purine biosynthesis.
SQ   SEQUENCE   298 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQIVTKTDIA EYKLLSRGKV RDIYEVDAET LLIVTTDRMS AFDVIMGEPI PYKGVILNSI
     TLFWMERFAD LVPNHLIASD VKDFPQALHK YADMLEGRAV LVRKAAPLPV ECIVRGHITG
     SGWKDYQKTG MVCGHSLPAG LVESAKLETP LFTPSTKAEL GEHDENISVQ RARELVGDDV
     AAQIERLSIE IFSKGREYAE SRGIIIADTK FEFGIIDGAV ILIDEVLTPD SSRFWPVQGY
     QPGKSQPSFD KQYLRDWLSA QDWDKTPPAP ALPQDVITET RNKYAEAYSI LTGKTLNL
//

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