(data stored in SCRATCH3701 zone)

HOGENOM6: DESRD_1_PE2453

ID   DESRD_1_PE2453                       STANDARD;      PRT;   809 AA.
AC   DESRD_1_PE2453; C8X5Q8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (DESRD_1.PE2453).
GN   OrderedLocusNames=Dret_2473;
OS   DESULFOHALOBIUM RETBAENSE DSM 5692.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfohalobiaceae; Desulfohalobium.
OX   NCBI_TaxID=485915;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS DESRD_1.PE2453.
CC       Desulfohalobium retbaense DSM 5692, complete genome.
CC       complete genome.
CC   -!- ANNOTATIONS ORIGIN:C8X5Q8_DESRD
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C8X5Q8; -.
DR   EMBL; CP001734; ACV69755.1; -; Genomic_DNA.
DR   RefSeq; YP_003199333.1; NC_013223.1.
DR   STRING; C8X5Q8; -.
DR   GeneID; 8420335; -.
DR   GenomeReviews; CP001734_GR; Dret_2473.
DR   KEGG; drt:Dret_2473; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; DESRD_1.PE2453; -.
DR   PRODOM; DESRD_1_PE2453.
DR   SWISS-2DPAGE; DESRD_1_PE2453.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   809 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLQSIHIEEE IKKSYLEYSL SVIIGRALPD VRDGLKPVHR RILYAMHDLG NTYNRPYKKS
     ARIVGDVIGK YHPHGDAAVY DALVRMAQDF NMRHPLVDGQ GNFGSLDGDA PAAMRYTESR
     MARISGEFLA DIDKQTVNFR ANYDNTLHEP EVLPTKVPNL LVNGASGIAV GMATNIPPHN
     LGEVTDALLA LLDDPSLGLD QLLHYIKGPD FPTAALMYGR QGMRQAYATG RGSIKLRSRL
     HVEESKKGRE SIVITEIPFA LNKASLVEKI AQLVNEGKLE GISDLRDESD RNGIRIVIDL
     KRNTLSDIVI NTLYKYTALE TSYGINLLAV VNNRPQLLSL KQILELFLEH RKEVILRRSR
     YDLDKAEKRA HILEGLRIAL DNIDEVVRLI RASATPAEAK AGLMQRFELS EVQSQAILDM
     RLHRLTNLER DKLLEEYRAV LERIEYLKSI IEQSEVLRGV VRDELQELRK TFASPRRTEI
     LESDPNEIDI EDLIPDEEVV ITLTRNGYIK RTPLSAYQQQ KRGGKGVSGA NVAQKDFVTD
     LMTGTNHQYL LLFTNKGRMH QLKVYQIPEG RRTARGTHIA NLLPLDKEEY VATVLCMKDF
     DANHSFLFAT KKGMVKRSAV HLYRNYRPHG LIAVNLRDGD ELIAVREVDE ESEIFLITHH
     GVAIRFACSE VRSMGRGAAG VKGIALRQED AVVSCVIING DGRDQLLTVS EQGYGKRTAI
     DYYRQQSRGG KGIINMRLTS KTGGVLGAMM VDETDELIML TSMHKMLRIG TADIRICGRA
     TQGVKLVSLD SEATVVCFDR IVSEEALSS
//

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