(data stored in ACNUC7421 zone)

HOGENOM: DICZE_1_PE1006

ID   DICZE_1_PE1006                       STANDARD;      PRT;   284 AA.
AC   DICZE_1_PE1006; C6CNH8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Pantothenate synthetase; Short=PS; EC=6.3.2 1;AltName:
DE   Full=Pantoate--beta-alanine ligase;AltName: Full=Pantoate-activating
DE   enzyme; (DICZE_1.PE1006).
GN   Name=panC; OrderedLocusNames=Dd1591_1027;
OS   DICKEYA ZEAE ECH1591.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Dickeya.
OX   NCBI_TaxID=561229;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS DICZE_1.PE1006.
CC       Dickeya zeae Ech1591 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C6CNH8_DICZE
CC   -!- FUNCTION: Catalyzes the condensation of pantoate with beta-alanine
CC       in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + (R)-pantoate + beta-alanine = AMP +
CC       diphosphate + (R)-pantothenate.
CC   -!- PATHWAY: Cofactor biosynthesis; (R)-pantothenate biosynthesis;
CC       (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- MISCELLANEOUS: The reaction proceeds by a bi uni uni bi ping pong
CC       mechanism (By similarity).
CC   -!- SIMILARITY: Belongs to the pantothenate synthetase family.
CC   -!- GENE_FAMILY: HOG000175516 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C6CNH8; -.
DR   EMBL; CP001655; ACT05900.1; -; Genomic_DNA.
DR   RefSeq; YP_003003379.1; NC_012912.1.
DR   STRING; C6CNH8; -.
DR   GeneID; 8120300; -.
DR   GenomeReviews; CP001655_GR; Dd1591_1027.
DR   KEGG; dze:Dd1591_1027; -.
DR   OMA; LNMPIQI; -.
DR   ProtClustDB; PRK00380; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004592; F:pantoate-beta-alanine ligase activity; IEA:HAMAP.
DR   GO; GO:0015940; P:pantothenate biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00158; PanC; 1; -.
DR   InterPro; IPR004821; Cyt_trans-rel.
DR   InterPro; IPR003721; Pantoate_ligase.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   Gene3D; G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.
DR   PANTHER; PTHR21299:SF1; Pantoate_ligase; 1.
DR   Pfam; PF02569; Pantoate_ligase; 1.
DR   TIGRFAMs; TIGR00125; Cyt_tran_rel; 1.
DR   TIGRFAMs; TIGR00018; PanC; 1.
DR   HOGENOMDNA; DICZE_1.PE1006; -.
KW   ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding;
KW   Pantothenate biosynthesis.
SQ   SEQUENCE   284 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLIIETPVLL RRELRRWRQY GKRIALVPTM GNLHDGHLTL VDEARARADI VVVSIFVNPL
     QFERADDLAR YPRTLQEDCE KLTRRGVDLV FAPAPDTLYP NGLQQQTFVE VPGLSQMLEG
     ASRPGHFRGV ATVVSKLFNL VQPDVACFGE KDYQQLALIR QMVADMDYDI SIVGVPTVRA
     KDGLALSSRN GYLTAEERQQ APQLRRIMNE MVEQLSNGDR QIDDMLASAS DALRNAGFTP
     DELFIRDAAT LQPLTIDSTR AVVLMAAWLG KARLIDNQQV DLTI
//

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