(data stored in SCRATCH zone)

HOGENOM: ECO1A_1_PE1011

ID   ECO1A_1_PE1011                       STANDARD;      PRT;   123 AA.
AC   ECO1A_1_PE1011; C8ULL5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Crossover junction endodeoxyribonuclease rusA; EC=3.1.22 4;
DE   (ECO1A_1.PE1011).
GN   OrderedLocusNames=ECO111_1065;
OS   ESCHERICHIA COLI O111:H- STR. 11128.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585396;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ECO1A_1.PE1011.
CC       Escherichia coli O111:H- str. 11128, complete genome.
CC       1..66570 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:C8ULL5_ECO1A
CC   -!- FUNCTION: Endonuclease that resolves Holliday junction
CC       intermediates made during homologous genetic recombination and DNA
CC       repair. Exhibits sequence and structure-selective cleavage of
CC       four-way DNA junctions, where it introduces symmetrical nicks in
CC       two strands of the same polarity at the 5' side of dinucleotides.
CC       Corrects the defects in genetic recombination and DNA repair
CC       associated with inactivation of ruvAB or ruvC (By similarity).
CC   -!- CATALYTIC ACTIVITY: Endonucleolytic cleavage at a junction such as
CC       a reciprocal single-stranded crossover between two homologous DNA
CC       duplexes (Holliday junction).
CC   -!- SIMILARITY: Belongs to the rusA family.
CC   -!- GENE_FAMILY: HOG000119986 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C8ULL5; -.
DR   EMBL; AP010960; BAI35015.1; -; Genomic_DNA.
DR   RefSeq; YP_003233566.1; NC_013364.1.
DR   ProteinModelPortal; C8ULL5; -.
DR   STRING; C8ULL5; -.
DR   EnsemblBacteria; EBESCT00000183064; EBESCP00000171144; EBESCG00000181686.
DR   GeneID; 8484550; -.
DR   GenomeReviews; AP010960_GR; ECO111_1065.
DR   KEGG; eoi:ECO111_1065; -.
DR   GeneTree; EBGT00050000009484; -.
DR   ProtClustDB; CLSK879876; -.
DR   GO; GO:0008821; F:crossover junction endodeoxyribonuclease activity; IEA:EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   InterPro; IPR016281; Endonuclease_RusA.
DR   InterPro; IPR008822; Endonuclease_RusA-like.
DR   Gene3D; G3DSA:3.30.1330.70; Endonuclease_RusA-like; 1.
DR   Pfam; PF05866; RusA; 1.
DR   PIRSF; PIRSF001007; RusA; 1.
DR   SUPFAM; SSF103084; RusA-like; 1.
DR   HOGENOMDNA; ECO1A_1.PE1011; -.
KW   Complete proteome; DNA damage; DNA repair; Endonuclease; Hydrolase;
KW   Nuclease.
SQ   SEQUENCE   123 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRIEFVLPYP PTVNTYWRRR GSTYFVSKAG ERYRRAVALI VRQQRLKLSL SGRLAIKIIA
     EPPDKRRRDL DNILKAPLDA LTHAEVLIDD EQFDEINIVR GQPVPGGRLG VKIYEIRGGN
     DGA
//

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