(data stored in ACNUC7421 zone)

HOGENOM: ECO26_1_PE1010

ID   ECO26_1_PE1010                       STANDARD;      PRT;   400 AA.
AC   ECO26_1_PE1010; C8TM47;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Nicotinate phosphoribosyltransferase; Short=NAPRTase;
DE   EC=2.4.2 11; (ECO26_1.PE1010).
GN   Name=pncB; OrderedLocusNames=ECO26_1058;
OS   ESCHERICHIA COLI O26:H11 STR. 11368.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=573235;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ECO26_1.PE1010.
CC       Escherichia coli O26:H11 str. 11368, complete genome.
CC       1..66570 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:C8TM47_ECO26
CC   -!- CATALYTIC ACTIVITY: Nicotinate D-ribonucleotide + diphosphate =
CC       nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.
CC   -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-
CC       ribonucleotide from nicotinate: step 1/1.
CC   -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate
CC       ribonucleotide from nicotinate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the NAPRTase family.
CC   -!- GENE_FAMILY: HOG000284928 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C8TM47; -.
DR   EMBL; AP010953; BAI24374.1; -; Genomic_DNA.
DR   RefSeq; YP_003228114.1; NC_013361.1.
DR   ProteinModelPortal; C8TM47; -.
DR   SMR; C8TM47; 3-385.
DR   STRING; C8TM47; -.
DR   EnsemblBacteria; EBESCT00000170797; EBESCP00000163612; EBESCG00000170691.
DR   GeneID; 8480536; -.
DR   GenomeReviews; AP010953_GR; ECO26_1058.
DR   KEGG; eoj:ECO26_1058; -.
DR   GeneTree; EBGT00050000010764; -.
DR   ProtClustDB; PRK05321; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004516; F:nicotinate phosphoribosyltransferase activity; IEA:HAMAP.
DR   GO; GO:0004514; F:nicotinate-nucleotide diphosphorylase (carboxylating) activity; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:HAMAP.
DR   GO; GO:0019357; P:nicotinate nucleotide biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00570; NAPRTase; 1; -.
DR   InterPro; IPR006406; Nic_PRibTrfase.
DR   InterPro; IPR015977; Nic_PRibTrfase-like.
DR   InterPro; IPR007229; Nic_PRibTrfase-rel.
DR   InterPro; IPR002638; Quinolinate_PRibosylTrfase_C.
DR   Pfam; PF04095; NAPRTase; 1.
DR   PIRSF; PIRSF000484; NAPRT; 1.
DR   SUPFAM; SSF51690; Q_phspho_trans; 1.
DR   TIGRFAMs; TIGR01514; NAPRTase; 1.
DR   HOGENOMDNA; ECO26_1.PE1010; -.
KW   nicotinate phosphoribosyltransferase;
KW   Complete proteome; Cytoplasm; Glycosyltransferase;
KW   Pyridine nucleotide biosynthesis; Transferase.
SQ   SEQUENCE   400 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTQFASPVLH SLLDTDAYKL HMQQAVFHHY YDVHVAAEFR CRGDDLLGIY ADAIREQIQA
     MQHLRLQDDE YQWLSALPFF KADYLNWLRE FRFNPEQVTV SNDNGKLDIR LSGPWREVIL
     WEVPLLAVIS EMVHRYRSPQ ADVAQALDTL ESKLVDFSAL TAGLDMSRFH LMDFGTRRRF
     SREVQETIVK RLQQESWFVG TSNYDLARRL SLTPMGTQAH EWFQAHQQIS PDLANSQRAA
     LAAWLEEYPD QLGIALTDCI TMDAFLRDFG VEFASRYQGL RHDSGDPVEW GEKAIAHYEK
     LGIDPQSKTL VFSDNLDLRK AVELYRHFSS RVQLSFGIGT RLTCDIPQVK PLNIVIKLVE
     CNGKPVAKLS DSPGKTICHD KAFVRALRKA FDLPHIKKAS
//

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