(data stored in ACNUC7421 zone)

HOGENOM: ECO45_1_PE4520

ID   ECO45_1_PE4520                       STANDARD;      PRT;   371 AA.
AC   ECO45_1_PE4520; B7MMH6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylthioribose-1-phosphate isomerase; Short=M1Pi;
DE   Short=MTR-1-P isomerase; EC=5.3.1 23;AltName:
DE   Full=S-methyl-5-thioribose-1-phosphate isomerase; (ECO45_1.PE4520).
GN   Name=mtnA; OrderedLocusNames=ECS88_4902;
OS   ESCHERICHIA COLI S88.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585035;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ECO45_1.PE4520.
CC       Escherichia coli S88, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:MTNA_ECO45
CC   -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1-
CC       phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-methyl-5-thio-alpha-D-ribose 1-phosphate =
CC       S-methyl-5-thio-D-ribulose 1-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via
CC       salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose
CC       1-phosphate: step 1/6.
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family. MtnA subfamily.
CC   -!- GENE_FAMILY: HOG000224730 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B7MMH6; -.
DR   EMBL; CU928161; CAR06048.1; -; Genomic_DNA.
DR   RefSeq; YP_002394376.1; NC_011742.1.
DR   ProteinModelPortal; B7MMH6; -.
DR   SMR; B7MMH6; 7-359.
DR   STRING; B7MMH6; -.
DR   EnsemblBacteria; EBESCT00000139999; EBESCP00000130876; EBESCG00000138521.
DR   GeneID; 7129625; -.
DR   GenomeReviews; CU928161_GR; ECS88_4902.
DR   GeneTree; EBGT00050000013712; -.
DR   OMA; RPRNQGA; -.
DR   ProtClustDB; CLSK2411299; -.
DR   BioCyc; ECOL585035:ECS88_4902-MON; -.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_01678; Salvage_MtnA; 1; -.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR005251; IF-2BI_MTNA.
DR   InterPro; IPR011559; Initiation_fac_2B_a/b/d.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   TIGRFAMs; TIGR00524; EIF-2B_rel; 1.
DR   TIGRFAMs; TIGR00512; Salvage_mtnA; 1.
DR   HOGENOMDNA; ECO45_1.PE4520; -.
KW   Amino-acid biosynthesis; Complete proteome; Isomerase;
KW   Methionine biosynthesis.
SQ   SEQUENCE   371 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNIKGKHYRT VWVSGDGKAV EIIDQTKLPF KFEVVALTSA EMAATAIQDM WVRGAPLIGV
     VAAYGIALGM NHDASDMGLQ RYYDLLIKTR PTAINLKWAL DRMIDTLKDL CVSERKDVAW
     ALAAEIAEED VALCEQIGLH GAEVIREIAQ KKPAGSVVNI LTHCNAGWLA TVDWGTALSP
     IYKAHENGIP VHVWVDETRP RNQGGLTAFE LGSHGIPHTL IADNAGGHLM QHGDVDLCIV
     GTDRTTARGD VCNKIGTYLK ALAAHDNHVP FYVALPSPTI DWTIEDGKSI PIEQRDGKEQ
     SHVYGINPQG ELSWVNTAPE GTRCGNYAFD VTPARYITGF ITERGVCAAS KSALADMFAD
     LKSKALQGEQ H
//

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