(data stored in SCRATCH zone)

HOGENOM: ECO81_1_PE1010

ID   ECO81_1_PE1010                       STANDARD;      PRT;   306 AA.
AC   ECO81_1_PE1010; B7MPT2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Curved DNA-binding protein; (ECO81_1.PE1010).
GN   Name=cbpA; OrderedLocusNames=ECED1_1077;
OS   ESCHERICHIA COLI ED1A.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585397;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ECO81_1.PE1010.
CC       Escherichia coli ED1a, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:CBPA_ECO81
CC   -!- FUNCTION: DNA-binding protein that preferentially recognizes a
CC       curved DNA sequence. It is probably a functional analog of DnaJ;
CC       displays overlapping activities with DnaJ, but functions under
CC       different conditions, probably acting as a molecular chaperone in
CC       an adaptive response to environmental stresses other than heat
CC       shock. Lacks autonomous chaperone activity; binds native
CC       substrates and targets them for recognition by DnaK. Its activity
CC       is inhibited by the binding of CbpM (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid (By similarity).
CC   -!- SIMILARITY: Contains 1 J domain.
CC   -!- GENE_FAMILY: HOG000226716 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B7MPT2; -.
DR   EMBL; CU928162; CAR07278.1; -; Genomic_DNA.
DR   RefSeq; YP_002397100.1; NC_011745.1.
DR   ProteinModelPortal; B7MPT2; -.
DR   SMR; B7MPT2; 2-76, 114-303.
DR   STRING; B7MPT2; -.
DR   EnsemblBacteria; EBESCT00000141857; EBESCP00000133087; EBESCG00000143968.
DR   GeneID; 7139310; -.
DR   GenomeReviews; CU928162_GR; ECED1_1077.
DR   GeneTree; EBGT00050000009076; -.
DR   OMA; KVANDST; -.
DR   ProtClustDB; PRK10266; -.
DR   BioCyc; ECOL585397:ECED1_1077-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0031072; F:heat shock protein binding; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   HAMAP; MF_01154; CbpA; 1; -.
DR   InterPro; IPR023859; DNA-bd_curved-DNA.
DR   InterPro; IPR002939; DnaJ_C.
DR   InterPro; IPR001623; DnaJ_N.
DR   InterPro; IPR018253; Heat_shock_DnaJ_CS.
DR   InterPro; IPR008971; HSP40/DnaJ_pept-bd.
DR   InterPro; IPR003095; Hsp_DnaJ.
DR   Gene3D; G3DSA:1.10.287.110; DnaJ_N; 1.
DR   Pfam; PF00226; DnaJ; 1.
DR   Pfam; PF01556; DnaJ_C; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; DnaJ_N; 1.
DR   SUPFAM; SSF49493; HSP40_DnaJ_pep; 2.
DR   PROSITE; PS00636; DNAJ_1; 1.
DR   PROSITE; PS50076; DNAJ_2; 1.
DR   HOGENOMDNA; ECO81_1.PE1010; -.
KW   curved DNA-binding protein CbpA;
KW   Chaperone; Complete proteome; Cytoplasm; DNA-binding.
SQ   SEQUENCE   306 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MELKDYYAIM GVKPTDDLKT IKTAYRRLAR KYHPDVSKEP DAEARFKEVA EAWEVLSDEQ
     RRAEYDQMWQ HRNDPQFNRQ FHHGDGQSFN AEDFDDIFSS IFGQHARQSR QRPATRGHDI
     EIEVAVFLEE TLTEHKRTIS YNLPVYNAFG MIEQEIPKTL NVKIPAGVGN GQRIRLKGQG
     TPGENGGPNG DLWLVIHIAP HPLFDIVGQD LEIVVPVSPW EAALGTKVTV PTLKESILLT
     IPPGSQAGQR LRVKGKGLVS KKQTGDLYAV LKIVMPPKPD ENTAALWQQL ADAQSSFDPR
     KDWGKA
//

If you have problems or comments...

PBIL Back to PBIL home page