(data stored in ACNUC9435 zone)

HOGENOM: ECODH_1_PE1004

ID   ECODH_1_PE1004                       STANDARD;      PRT;   196 AA.
AC   ECODH_1_PE1004; B1X9C9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Probable malonic semialdehyde reductase RutE; EC=1.1.1 298;
DE   (ECODH_1.PE1004).
GN   Name=rutE; OrderedLocusNames=ECDH10B_1080;
OS   ESCHERICHIA COLI STR. K-12 SUBSTR. DH10B.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=316385;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ECODH_1.PE1004.
CC       Escherichia coli str. K-12 substr. DH10B, complete genome.
CC       chromosome, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:RUTE_ECODH
CC   -!- FUNCTION: May reduce toxic product malonic semialdehyde to 3-
CC       hydroxypropionic acid, which is excreted (By similarity).
CC   -!- CATALYTIC ACTIVITY: 3-hydroxypropanoate + NADP(+) = 3-
CC       oxopropanoate + NADPH.
CC   -!- COFACTOR: FMN (Potential).
CC   -!- INDUCTION: Up-regulated by the nitrogen regulatory protein C (NtrC
CC       also called GlnG) and repressed by RutR (Potential).
CC   -!- SIMILARITY: Belongs to the nitroreductase family. HadB/RutE
CC       subfamily.
CC   -!- GENE_FAMILY: HOG000236370 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B1X9C9; -.
DR   EMBL; CP000948; ACB02209.1; -; Genomic_DNA.
DR   RefSeq; YP_001729987.1; NC_010473.1.
DR   ProteinModelPortal; B1X9C9; -.
DR   SMR; B1X9C9; 9-195.
DR   STRING; B1X9C9; -.
DR   EnsemblBacteria; EBESCT00000011845; EBESCP00000011373; EBESCG00000010907.
DR   GeneID; 6059777; -.
DR   GenomeReviews; CP000948_GR; ECDH10B_1080.
DR   KEGG; ecd:ECDH10B_1080; -.
DR   GeneTree; EBGT00050000010805; -.
DR   OMA; MGPTSAN; -.
DR   ProtClustDB; PRK05365; -.
DR   BioCyc; ECOL316385:ECDH10B_1080-MON; -.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   HAMAP; MF_01204; Oxidoreductase_RutE_HadB; 1; -.
DR   InterPro; IPR000415; Nitroreductase-like.
DR   InterPro; IPR023936; Nitroreductase_RutE.
DR   Gene3D; G3DSA:3.40.109.10; G3DSA:3.40.109.10; 1.
DR   Pfam; PF00881; Nitroreductase; 1.
DR   SUPFAM; SSF55469; Nitroreductase; 1.
DR   HOGENOMDNA; ECODH_1.PE1004; -.
KW   hypothetical protein;
KW   Complete proteome; Flavoprotein; FMN; NAD; NADP; Oxidoreductase.
SQ   SEQUENCE   196 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNEAVSPGAL STLFTDARTH NGWRETPVSD ETLREIYALM KWGPTSANCS PARIVFTRTA
     EGKERLRPAL SSGNLQKTLT APVTAIVAWD SEFYERLPLL FPHGDARSWF TSSPQLAEET
     AFRNSSMQAA YLIVACRALG LDTGPMSGFD RQHVDDAFFT GSTLKSNLLI NIGYGDSSKL
     YARLPRLSFE EACGLL
//

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