(data stored in ACNUC9435 zone)

HOGENOM: ECOK1_1_PE1

ID   ECOK1_1_PE1                          STANDARD;      PRT;   820 AA.
AC   ECOK1_1_PE1; A1A755;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Bifunctional aspartokinase I/homeserine dehydrogenase I;
DE   (ECOK1_1.PE1).
GN   Name=thrA; OrderedLocusNames=Ecok1_00010; ORFNames=APECO1_1976;
OS   ESCHERICHIA COLI APEC O1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=405955;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ECOK1_1.PE1.
CC       Escherichia coli APEC O1, complete genome.
CC       chromosome, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:A1A755_ECOK1
CC   -!- GENE_FAMILY: HOG000271593 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A1A755; -.
DR   EMBL; CP000468; ABI99494.1; -; Genomic_DNA.
DR   RefSeq; YP_851209.2; NC_008563.1.
DR   ProteinModelPortal; A1A755; -.
DR   STRING; A1A755; -.
DR   EnsemblBacteria; EBESCT00000038425; EBESCP00000036942; EBESCG00000037475.
DR   GeneID; 4491344; -.
DR   GenomeReviews; CP000468_GR; Ecok1_00010.
DR   KEGG; ecv:APECO1_1976; -.
DR   eggNOG; COG0527; -.
DR   GeneTree; EBGT00050000009086; -.
DR   OMA; GANEMNI; -.
DR   ProtClustDB; PRK09436; -.
DR   GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR   GO; GO:0004072; F:aspartate kinase activity; IEA:InterPro.
DR   GO; GO:0004412; F:homoserine dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0009067; P:aspartate family amino acid biosynthetic process; IEA:InterPro.
DR   InterPro; IPR002912; ACT-bd.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR005106; Asp/hSer_DH_NAD-bd.
DR   InterPro; IPR001341; Asp_kinase_dom.
DR   InterPro; IPR018042; Aspartate_kinase_CS.
DR   InterPro; IPR011147; Bifunc_aspartokin/hSer_DH.
DR   InterPro; IPR001342; HDH_cat.
DR   InterPro; IPR019811; HDH_CS.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.1160.10; Aa_kinase; 2.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   Pfam; PF01842; ACT; 2.
DR   Pfam; PF00742; Homoserine_dh; 1.
DR   Pfam; PF03447; NAD_binding_3; 1.
DR   PIRSF; PIRSF000727; ThrA; 1.
DR   SUPFAM; SSF53633; Aa_kinase; 1.
DR   TIGRFAMs; TIGR00657; Asp_kinases; 1.
DR   PROSITE; PS00324; ASPARTOKINASE; 1.
DR   PROSITE; PS01042; HOMOSER_DHGENASE; 1.
DR   HOGENOMDNA; ECOK1_1.PE1; -.
KW   Complete proteome; Kinase; Transferase.
SQ   SEQUENCE   820 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MRVLKFGGTS VANAERFLRV ADILESNARQ GQVATVLSAP AKITNHLVAM IEKTISGQDA
     LPNISDAERI FAELLTGLAA AQPGFPLAQL KTFVDQEFAQ IKHVLHGISL LGQCPDSINA
     ALICRGEKMS IAIMAGVLEA RGHNVTVIDP VEKLLAVGHY LESTVDIAES TRRIAASRIP
     ADHMVLMAGF TAGNEKGELV VLGRNGSDYS AAVLAACLRA DCCEIWTDVD GVYTCDPRQV
     PDARLLKSMS YQEAMELSYF GAKVLHPRTI TPIAQFQIPC LIKNTGNPQA PGTLIGASRD
     EDELPVKGIS NLNNMAMFSV SGPGMKGMVG MAARVFAAMS RARISVVLIT QSSSEYSISF
     CVPQSDCVRA ERAMQEEFYL ELKEGLLEPL AVTERLAIIS VVGDGMRTLR GISAKFFAAL
     ARANINIVAI AQGSSERSIS VVVNNDDATT GVRVTHQMLF NTDQVIEVFV IGVGGVGGAL
     LEQLKRQQSW LKNKHIDLRV CGVANSKALL TNVHGLNLEN WQEELAQAKE PFNLGRLIRL
     VKEYHLLNPV IVDCTSSQAV ADQYADFLRE GFHVVTPNKK ANTSSMDYYH QLRYAAEKSR
     RKFLYDTNVG AGLPVIENLQ NLLNAGDELM KFSGILSGSL SYIFGKLDEG MSFSEATTLA
     REMGYTEPDP RDDLSGMDVA RKLLILARET GRELELADIE IEPVLPAEFN AEGDVAAFMA
     NLSQLDDLFA ARVAKARDEG KVLRYVGNID EDGVCRVKIA EVDGNDPLFK VKNGENALAF
     YSHYYQPLPL VLRGYGAGND VTAAGVFADL LRTLSWKLGV
//

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