(data stored in SCRATCH zone)

HOGENOM: EDWTF_1_PE1009

ID   EDWTF_1_PE1009                       STANDARD;      PRT;   347 AA.
AC   EDWTF_1_PE1009; E0T3R2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Phosphoribosylformylglycinamidine cyclo-ligase; EC=6.3.3
DE   1;AltName: Full=AIR synthase;AltName: Full=AIRS;AltName:
DE   Full=Phosphoribosyl-aminoimidazole synthetase; (EDWTF_1.PE1009).
GN   Name=purM; OrderedLocusNames=ETAF_1013;
OS   EDWARDSIELLA TARDA FL6-60.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Edwardsiella.
OX   NCBI_TaxID=718251;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS EDWTF_1.PE1009.
CC       Edwardsiella tarda (strain FL6-60) chromosome, complete sequence.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E0T3R2_EDWTF
CC   -!- CATALYTIC ACTIVITY: ATP + 2-(formamido)-N(1)-(5-phospho-D-
CC       ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-
CC       ribosyl)imidazole.
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway;
CC       5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-
CC       phospho-D-ribosyl)glycinamide: step 2/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the AIR synthase family.
CC   -!- GENE_FAMILY: HOG000229090 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E0T3R2; -.
DR   EMBL; CP002154; ADM41132.1; -; Genomic_DNA.
DR   ProteinModelPortal; E0T3R2; -.
DR   GenomeReviews; CP002154_GR; ETAF_1013.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004641; F:phosphoribosylformylglycinamidine cyclo-ligase activity; IEA:EC.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00741_B; AIRS_B; 1; -.
DR   InterPro; IPR000728; AIR_synth.
DR   InterPro; IPR010918; AIR_synth_C.
DR   InterPro; IPR004733; PurM_cligase.
DR   InterPro; IPR016188; PurM_N-like.
DR   Pfam; PF00586; AIRS; 1.
DR   Pfam; PF02769; AIRS_C; 1.
DR   SUPFAM; SSF56042; AIR_synth_C; 1.
DR   SUPFAM; SSF55326; PurM_N-like; 1.
DR   TIGRFAMs; TIGR00878; PurM; 1.
DR   HOGENOMDNA; EDWTF_1.PE1009; -.
KW   ADM41132.1000068575old_1320000031;
KW   ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding;
KW   Purine biosynthesis.
SQ   SEQUENCE   347 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDKTALSYK DAGVDIDAGN ALVDRIKGVV KETRRPEVMG GLGGFGALCA LPQKYREPVL
     VSGTDGVGTK LRLAMDLQRH DSIGIDLVAM CVNDLVVQGA EPLFFLDYYA TGKLDVDTAA
     SVIGGIAAGC KQAGCALVGG ETAEMPGMYH GEDYDVAGFC VGVVEKSQII DGSQVRPGDA
     LIALAASGPH SNGYSLIRKI LEVSGCDPRT TMLAGRPLAD HLLAPTRIYV AACLDLIASH
     EVHALAHLTG GGFWENIPRV LPAGAKAVID EGSWQWPAVF DWLQQTGNVS RREMYRTFNC
     GVGMVIALPQ AQVDSALARL SQSGEQAWLL GHIAEAQGDE PQVEILR
//

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