(data stored in SCRATCH3701 zone)

HOGENOM6: EDWTF_1_PE2091

ID   EDWTF_1_PE2091                       STANDARD;      PRT;   878 AA.
AC   EDWTF_1_PE2091; E0T379;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (EDWTF_1.PE2091).
GN   OrderedLocusNames=ETAF_2108;
OS   EDWARDSIELLA TARDA FL6-60.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Edwardsiella.
OX   NCBI_TaxID=718251;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS EDWTF_1.PE2091.
CC       Edwardsiella tarda (strain FL6-60) chromosome, complete sequence.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E0T379_EDWTF
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E0T379; -.
DR   EMBL; CP002154; ADM42214.1; -; Genomic_DNA.
DR   GenomeReviews; CP002154_GR; ETAF_2108.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; EDWTF_1.PE2091; -.
DR   PRODOM; EDWTF_1_PE2091.
DR   SWISS-2DPAGE; EDWTF_1_PE2091.
KW   ADM42214.1000068575old_1320000031;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   878 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDLAREITP VNIEEELKNS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF AMNVLGNDWN
     KPYKKSARVV GDVIGKYHPH GDRAVYDTIV RMAQPFSLRY MLVDGQGNFG SIDGDSAAAM
     RYTEVRMAKI AHELLADLDK ETVDYVPNYD GTEQIPDVLP TKVPNLLVNG SAGIAVGMAT
     NIPPHNLTEV INGCLAYIDD ENITIEGLME HIPGPDFPTA AIINGRRGIE EAYRTGRGKI
     YVRARAEIEV DDKNGRETIV VHEIPYQVNK ARLIEKIAEL VKEKRVEGIS ALRDESDKDG
     MRIVIEVKRD AVGEVVLNNL YTQTQMQVSF GINMVALHQG QPKLLTLKEC LEAFVRHRRE
     VVTRRTIFEL RKARERAHIL EGLAIALVNI DPIIELIRRA PTPAEAKAAL VSQAWALGNV
     AAMLARAGDD AARPEWLEPQ YGIRDGHYHL TEQQAQAILD LRLQKLTGLE HEKLLDEYKA
     LLEQIAALIF ILQSPERLME VIREELIAIR EQFGDARRTE ITANTADINI EDLIEQEDVV
     VTLSHQGYVK YQPLSDYEAQ RRGGKGKSAA RIKEEDFIDR LLVANTHDTI LCFSSRGRMY
     WMKVYQLPEA SRGARGRPII NLLPLEADER ITAILPVREY AEGVNVFMAT ASGTVKKTAL
     TEFSRPRAAG IIAVNLNYGD ELIGVDLTDG NDEVMLFSAA GKVVRFKEDA VRAMGRTATG
     VRGIKLAGED RVVSLIVPHG EGAILTVTQN GYGKRSGVAE YPTKSRATQG VISIKVTERN
     GSVVGAVQVE DCDQIMMITD AGTLVRTRVS EVSIVGRNTQ GVILIRTAED EHVVGLQRVV
     EPVDDEDLDS IDGSAAEGDD EIVPEVESDD DAAEDDAE
//

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