(data stored in SCRATCH3701 zone)

HOGENOM6: EHRCR_1_PE818

ID   EHRCR_1_PE818                        STANDARD;      PRT;   898 AA.
AC   EHRCR_1_PE818; Q2GFY0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (EHRCR_1.PE818).
GN   Name=gyrA; OrderedLocusNames=ECH_0858;
OS   EHRLICHIA CHAFFEENSIS STR. ARKANSAS.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Ehrlichia.
OX   NCBI_TaxID=205920;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS EHRCR_1.PE818.
CC       Ehrlichia chaffeensis str. Arkansas, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:Q2GFY0_EHRCR
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q2GFY0; -.
DR   EMBL; CP000236; ABD44722.1; -; Genomic_DNA.
DR   RefSeq; YP_507653.1; NC_007799.1.
DR   ProteinModelPortal; Q2GFY0; -.
DR   STRING; Q2GFY0; -.
DR   GeneID; 3927477; -.
DR   GenomeReviews; CP000236_GR; ECH_0858.
DR   KEGG; ech:ECH_0858; -.
DR   TIGR; ECH_0858; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q2GFY0; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; EHRCR_1.PE818; -.
DR   PRODOM; EHRCR_1_PE818.
DR   SWISS-2DPAGE; EHRCR_1_PE818.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   898 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDVNNVIPV SIEQELEDSY LSYAMSVIVS RAIPDIRDGL KPVHRRILYS MYKSGYDYGK
     PYKKAARVVG DVMGKYHPHA DAAIYDSLVR MAQDFSLLLP LIDSQGNFGS IDGDPPASMR
     YTEARLAKAA HFLLNDIDED TVDFRPNYDE NEVEPVVLPA EFPNILVNGA GGVAVGMSTN
     IPSHNLGEVI DACIAYIDNP EITFDELINI VRGPDFPTGG TILGDAGIRS AFMTGKGTII
     IQGKTHLEDL PSGKQAIIID EIPYQVNKAK LIERIHELIK EKKIEGILDL RDESNKMGIR
     VAIELKKQVS HQVILNQILG LTPLRTSFSI NTLVLDNNKP KVMSLPDIIS TFVEYRKEVL
     TRRTQFRLRK VRERAHLYIG MYIAVLNIDK VIAIIRSSRD TAEATKRLLE CKWDALTSVR
     EMIELVADSK SIVIDNVCQL TGVQVKSILE MKLQRLTNLE KEKLELDLKS MVSMIKQYTE
     LLKNKESLLQ LIKDGFKEIK AKLAVPRRTT IDYSHFETDI EDLIPKEDMV VTVTMSGYIK
     RAKLSNYRAQ KRGGKGRIGQ AIKEEDVITN LFVVNTHTSV LFFSNIGRVY KLKVYKLPLG
     EPTSRGRSLV NIFPLSENES ITSVMPLPDN VEDAEILNIV FATASGNLRR NALSDFQYVP
     SNGKIAMVLD TGDTLISVKV CKEEDHVLLS TRLGKSIRFS VSNVRQFKGR MSDGVRAIKL
     SSDDNVISMS VLLAMDIDSE KKDLYLKVPL DKRMCVKEEG VVNGGIAKIL CDLGLEQDIF
     VTMVQNEQFI LTVTENGFGK RTSAYEYRTT LRGGVGVVNI LTTARNGNVV ASFPVESNDH
     IMLITDKGKL IRIAVSDIRI IGRSTQGVTL FKTEKREKVV SVAKIIDAKD NSDIDGNI
//

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