(data stored in SCRATCH3701 zone)

HOGENOM6: ENT38_2_PE2774

ID   ENT38_2_PE2774                       STANDARD;      PRT;   888 AA.
AC   ENT38_2_PE2774; A4WCN4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (ENT38_2.PE2774).
GN   OrderedLocusNames=Ent638_2799;
OS   ENTEROBACTER SP. 638.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=399742;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ENT38_2.PE2774.
CC       Enterobacter sp. 638, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A4WCN4_ENT38
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A4WCN4; -.
DR   EMBL; CP000653; ABP61464.1; -; Genomic_DNA.
DR   RefSeq; YP_001177515.1; NC_009436.1.
DR   STRING; A4WCN4; -.
DR   GeneID; 5112751; -.
DR   GenomeReviews; CP000653_GR; Ent638_2799.
DR   KEGG; ent:Ent638_2799; -.
DR   NMPDR; fig|399742.4.peg.2679; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; A4WCN4; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; ENT38_2.PE2774; -.
DR   PRODOM; ENT38_2_PE2774.
DR   SWISS-2DPAGE; ENT38_2_PE2774.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   888 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDLAREITP VNIEEELKSS YLDYAMSVIV GRALPDVRDG LKPVHRRVLY AMNVLGNDWN
     KAYKKSARVV GDVIGKYHPH GDTAVYDTIV RMAQPFSLRY MLVDGQGNFG SVDGDSAAAM
     RYTEIRMSKI AHELMADLEK DTVDFVDNYD GTERIPDVMP TKIPNLLVNG SSGIAVGMAT
     NIPPHNITEV INGCLAYIDD EEITVEGLME HIPGPDFPTA AIINGRRGIE EAYRTGRGKI
     YIRARAEVEA DAKTGRETII VHEIPYQVNK ARLIEKIAEL VKEKRVEGIS ALRDESDKDG
     MRIVIEIKRD AVGEVVLNNL YSQTQLQVSF GINMVALHHG QPKIMNLKDI LSAFVRHRRE
     VVTRRTIFEL RKARDRAHIL EALAVALANI DPIIELIRRA PTPAEAKAGL VAQPWALGNV
     SAMLERAGDD AARPEWLEPE FGVRDGQYYL TEQQAQAILD LRLQKLTGLE HEKLLDEYKE
     LLEQIAELLH ILGSADRLME VIREELELVR DQFGDARRTE ITANTSDINI EDLINREDVV
     VTLSHQGYVK YQPLTDYEAQ RRGGKGKSAA RIKEEDFIDR LLVANTHDTI LCFSSRGRLY
     WMKVYQLPEA SRGARGRPIV NLLPLEPNER ITAILPVREY EEGVNVFMAT ASGTVKKTAL
     TGFSRPRSAG IIAINLNEGD ELIGVDLTSG SDDVMLFSAA GKVVRFKENA VRAMGRTATG
     VRGIRLAGED SVVSLIIPRG EGAILTVTQN GYGKRTAEGE YPTKSRGTQG VISIKVTERN
     GSVVGAVQVD DCDQIMMITD AGTLVRTRVS EISVVGRNTQ GVILIRTAED ENVVGLQRVA
     EPVDDEELDS IDGSVAEGDD EIAPETETDE ADSEEADSDE DAADDADE
//

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