(data stored in SCRATCH3701 zone)

HOGENOM6: ENTCS_1_PE1469

ID   ENTCS_1_PE1469                       STANDARD;      PRT;   878 AA.
AC   ENTCS_1_PE1469; E3GB79;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (ENTCS_1.PE1469).
GN   OrderedLocusNames=Entcl_1487;
OS   ENTEROBACTER CLOACAE SCF1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
OX   NCBI_TaxID=701347;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ENTCS_1.PE1469.
CC       Enterobacter cloacae SCF1 chromosome, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:E3GB79_ENTCS
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E3GB79; -.
DR   EMBL; CP002272; ADO47748.1; -; Genomic_DNA.
DR   RefSeq; YP_003941032.1; NC_014618.1.
DR   GeneID; 9906526; -.
DR   GenomeReviews; CP002272_GR; Entcl_1487.
DR   KEGG; esc:Entcl_1487; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; ENTCS_1.PE1469; -.
DR   PRODOM; ENTCS_1_PE1469.
DR   SWISS-2DPAGE; ENTCS_1_PE1469.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   878 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDLAREITP VNIEEELKNS YLDYAMSVIV GRALPDVRDG LKPVHRRVLY AMNVLGNDWN
     KAYKKSARVV GDVIGKYHPH GDSAVYDTIV RMAQPFSLRY MLVDGQGNFG SIDGDSAAAM
     RYTEIRLAKI AHELMADLEK ETVDFVDNYD GTEKIPDVMP TKIPNLLVNG SSGIAVGMAT
     NIPPHNLTEV INGCLAYIDD ENISIEGLMA HIPGPDFPTA AIINGRRGIE EAYRTGRGKV
     YIRARAEVEA DAKTGRETII VHEIPYQVNK ARLIEKIAEL VKDKRVEGIS ALRDESDKDG
     MRIVIEVKRD AVGEVVLNNL YSQTQLQVSF GINMVALHHG QPKIMNLKEI LEAFVRHRRE
     VVTRRTIFEL RKARDRAHIL EALAIALANI DPIIELIRRA PTPAEAKAAL IARSWDLGNV
     SAMLERAGDD AARPEWLEPQ FGIHDGKYFL TEQQAQAILD LRLQKLTGLE HEKLLDEYKE
     LLEQIAELLH ILGSADRLME VIREELELIR EQFGDERRTE ITANSADINI EDLINQEDVV
     VTLSHQGYVK YQPLTDYEAQ RRGGKGKSAA RIKEEDFIDR LLVANTHDTI LCFSSRGRLY
     WMKVYQLPEA SRGARGRPIV NLLPLEADER ITAILPVREY EEGVNVFMAT ASGTVKKTAL
     TEFSRPRSAG IIAVNLNEGD ELIGVDLTSG SDEVMLFSAA GKVVRFKENA VRAMGRTATG
     VRGIKLAGED SVVSLIIPRG EGAILTVTQN GYGKRTAEGE YPTKSRGTQG VISIKVTERN
     GSVVGAVQVD DCDQIMMITD AGTLVRTRVS EISVVGRNTQ GVILIRTAED EHVVGLQRVA
     EPVDDEELDA IDGSAAEGDD EIAPETDSDD DVADDADE
//

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