(data stored in SCRATCH3701 zone)

HOGENOM6: ERYLH_1_PE1268

ID   ERYLH_1_PE1268                       STANDARD;      PRT;   931 AA.
AC   ERYLH_1_PE1268; Q2NAD1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Type IIA topoisomeraseA subunit; (ERYLH_1.PE1268).
GN   OrderedLocusNames=ELI_06340;
OS   ERYTHROBACTER LITORALIS HTCC2594.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Erythrobacteraceae; Erythrobacter.
OX   NCBI_TaxID=314225;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ERYLH_1.PE1268.
CC       Erythrobacter litoralis HTCC2594 chromosome, complete genome.
CC       pEp5, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:Q2NAD1_ERYLH
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q2NAD1; -.
DR   EMBL; CP000157; ABC63360.1; -; Genomic_DNA.
DR   RefSeq; YP_458157.1; NC_007722.1.
DR   STRING; Q2NAD1; -.
DR   GeneID; 3871187; -.
DR   GenomeReviews; CP000157_GR; ELI_06340.
DR   KEGG; eli:ELI_06340; -.
DR   NMPDR; fig|314225.3.peg.1788; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 5.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; ERYLH_1.PE1268; -.
DR   PRODOM; ERYLH_1_PE1268.
DR   SWISS-2DPAGE; ERYLH_1_PE1268.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   931 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGDYERIDIV DEMKTSYLDY AMSVIVSRAL PDVRDGLKPV HRRILFASKE GGFVAGRPYR
     KSAKIVGDVM GNYHPHGDSA IYDALARMTQ DWSLRVPLID GQGNFGSMDP DPPASMRYTE
     ARLAKVANAL LDDLDKDTVD FSDNYDGSLK EPQVLPARFP NLLVNGAGGI AVGMATNVPP
     HNLGEVIDGC LAFIANPAIT SEELMQYIPG PDFPTAPLIL GQAGARAAYT TGRGSVLMRA
     RHEIEEKRGD RKSIVFTSIP YQVGKSGLVE KIADAAKEKR IEGISDIRDE SSREGVRVVV
     DLKRDASPEV VLNQIWRYTP AQASFPANML AIKGGRPEVL TLRDIVQAFV SFREEVITRR
     TKFELNKARE RAHVLLGLVV AVSNLDEVVA MIRGSSNPQI AREKLRAKLW PIGDIAQYIQ
     LIEAIEPTAD QEGGTYQLSE RQVKAILDLR LHRLTALGRD EIGDELKELA SEIEEYLSIL
     ADRGKLFGVL QDELVEIKDE YATPRVSEIA PAWDGLEDED LIAREDMVVT VTHGGYIKRT
     PLATFRAQAR GGKGRSGMAT KDEDAVVELF VTSTHNPVLF FTNLGRVYRM KVWKLPEGSP
     TTKGRPMVNL LPLGDDERVT NVLSLPEDEE SWAALNIVFA TEQGMVRRNS MDAFTNVPTG
     GKYAMGFVEG TGDRLIGVEL LSEDQEIFLA SDAGKAIRFA ATDARETKSR TGIGVRGMTL
     KDDAKVVSMA VLDRLEQDME TREAYLRAAI WKNNDAEHTL DSDKVAQMEE GEEFILTLTA
     NGYGKISSAY EYRTIGRGGQ GLANIGTPDS NPERNGPVVA SFPVKHGSQL MLVTDQAKLI
     RMPIEFRHMV EGGFEEHKGW SVYGRTSSGV RVFDVAKGEH IVGAAIIDET EEPENEAEEA
     VVEGMVGRGA EETAPDPTMD RDSNEGEAPP E
//

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