(data stored in ACNUC7421 zone)

HOGENOM: ESCOL1_1_PE1329

ID   ESCOL1_1_PE1329                      STANDARD;      PRT;   457 AA.
AC   ESCOL1_1_PE1329; P21693;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=ATP-independent RNA helicase dbpA; EC=3.6.4 13;
DE   (ESCOL1_1.PE1329).
GN   Name=dbpA; OrderedLocusNames=b1343, JW1337;
OS   ESCHERICHIA COLI STR. K-12 SUBSTR. MG1655.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=511145;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ESCOL1_1.PE1329.
CC       Escherichia coli str. K-12 substr. MG1655 chromosome, complete genome.
CC       pEp5, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:DBPA_ECOLI
CC   -!- FUNCTION: Has a helix-destabilizing activity, which is not coupled
CC       to the ATPase activity. Can unwind the 23S rRNA as well as 16S
CC       rRNA. Exhibits an RNA-dependent ATPase activity, specifically
CC       stimulated by bacterial 23S rRNA. Could play a major role in
CC       ribosome assembly, specifically in the assembly process of the
CC       active center of 50S ribosomal subunits.
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DbpA
CC       subfamily.
CC   -!- SIMILARITY: Contains 1 helicase ATP-binding domain.
CC   -!- SIMILARITY: Contains 1 helicase C-terminal domain.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA36872.1; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000268809 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P21693; -.
DR   EMBL; X52647; CAA36872.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC74425.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA14946.1; -; Genomic_DNA.
DR   PIR; B64884; B64884.
DR   RefSeq; AP_001971.1; AC_000091.1.
DR   RefSeq; NP_415859.1; NC_000913.2.
DR   ProteinModelPortal; P21693; -.
DR   SMR; P21693; 1-456.
DR   IntAct; P21693; 6.
DR   EnsemblBacteria; EBESCT00000004879; EBESCP00000004879; EBESCG00000003984.
DR   EnsemblBacteria; EBESCT00000014318; EBESCP00000013609; EBESCG00000013380.
DR   GeneID; 947153; -.
DR   GenomeReviews; AP009048_GR; JW1337.
DR   GenomeReviews; U00096_GR; b1343.
DR   KEGG; ecj:JW1337; -.
DR   KEGG; eco:b1343; -.
DR   EchoBASE; EB0206; -.
DR   EcoGene; EG10210; dbpA.
DR   eggNOG; COG0513; -.
DR   GeneTree; EBGT00050000008320; -.
DR   OMA; KAREDDI; -.
DR   ProtClustDB; PRK11776; -.
DR   BioCyc; EcoCyc:EG10210-MON; -.
DR   BioCyc; MetaCyc:EG10210-MON; -.
DR   Genevestigator; P21693; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043531; F:ADP binding; IDA:EcoCyc.
DR   GO; GO:0005524; F:ATP binding; IDA:EcoCyc.
DR   GO; GO:0034459; F:ATP-dependent 3'-5' RNA helicase activity; IDA:EcoCyc.
DR   GO; GO:0033677; F:DNA/RNA helicase activity; IDA:EcoliWiki.
DR   GO; GO:0019843; F:rRNA binding; IDA:EcoCyc.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IMP:EcoCyc.
DR   InterPro; IPR005580; DbpA_RNA-bd.
DR   InterPro; IPR014001; DEAD-like_helicase.
DR   InterPro; IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF03880; DbpA; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
DR   HOGENOMDNA; ESCOL1_1.PE1329; -.
KW   ATP-binding; Complete proteome; Cytoplasm; Helicase; Hydrolase;
KW   Nucleotide-binding; Reference proteome; Ribosome biogenesis;
KW   RNA-binding.
SQ   SEQUENCE   457 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTAFSTLNVL PPAQLTNLNE LGYLTMTPVQ AAALPAILAG KDVRVQAKTG SGKTAAFGLG
     LLQQIDASLF QTQALVLCPT RELADQVAGE LRRLARFLPN TKILTLCGGQ PFGMQRDSLQ
     HAPHIIVATP GRLLDHLQKG TVSLDALNTL VMDEADRMLD MGFSDAIDDV IRFAPASRQT
     LLFSATWPEA IAAISGRVQR DPLAIEIDST DALPPIEQQF YETSSKGKIP LLQRLLSLHQ
     PSSCVVFCNT KKDCQAVCDA LNEVGQSALS LHGDLEQRDR DQTLVRFANG SARVLVATDV
     AARGLDIKSL ELVVNFELAW DPEVHVHRIG RTARAGNSGL AISFCAPEEA QRANIISDML
     QIKLNWQTPP ANSSIATLEA EMATLCIDGG KKAKMRPGDV LGALTGDIGL DGADIGKIAV
     HPAHVYVAVR QAVAHKAWKQ LQGGKIKGKT CRVRLLK
//

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