(data stored in ACNUC9435 zone)

HOGENOM: ETHAR1_1_PE1002

ID   ETHAR1_1_PE1002                      STANDARD;      PRT;   661 AA.
AC   ETHAR1_1_PE1002; E6U493;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA ligase; EC=6.5.1 2; (ETHAR1_1.PE1002).
GN   OrderedLocusNames=Ethha_1040;
OS   ETHANOLIGENENS HARBINENSE YUAN-3.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae;
OC   Ethanoligenens.
OX   NCBI_TaxID=663278;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ETHAR1_1.PE1002.
CC       Ethanoligenens harbinense YUAN-3 chromosome, complete genome.
CC       pEp5, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E6U493_ETHHY
CC   -!- CATALYTIC ACTIVITY: NAD(+) + (deoxyribonucleotide)(n) +
CC       (deoxyribonucleotide)(m) = AMP + nicotinamide nucleotide +
CC       (deoxyribonucleotide)(n+m).
CC   -!- SIMILARITY: Belongs to the NAD-dependent DNA ligase family.
CC   -!- GENE_FAMILY: HOG000218459 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E6U493; -.
DR   EMBL; CP002400; ADU26593.1; -; Genomic_DNA.
DR   RefSeq; YP_004091324.1; NC_014828.1.
DR   ProteinModelPortal; E6U493; -.
DR   GeneID; 10092006; -.
DR   GenomeReviews; CP002400_GR; Ethha_1040.
DR   KEGG; eha:Ethha_1040; -.
DR   GO; GO:0005622; C:intracellular; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003911; F:DNA ligase (NAD+) activity; IEA:HAMAP.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   HAMAP; MF_01588; DNA_ligase_A; 1; -.
DR   InterPro; IPR001357; BRCT.
DR   InterPro; IPR018239; DNA_ligase_AS.
DR   InterPro; IPR004150; DNA_ligase_OB.
DR   InterPro; IPR001679; DNAligase.
DR   InterPro; IPR013839; DNAligase_adenylation.
DR   InterPro; IPR013840; DNAligase_N.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR016027; NA-bd_OB-fold-like.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR004149; Znf_DNAligase_C4.
DR   Gene3D; G3DSA:2.40.50.140; OB_NA_bd_sub; 1.
DR   Pfam; PF00533; BRCT; 1.
DR   Pfam; PF01653; DNA_ligase_aden; 1.
DR   Pfam; PF03120; DNA_ligase_OB; 1.
DR   Pfam; PF03119; DNA_ligase_ZBD; 1.
DR   PIRSF; PIRSF001604; LigA; 1.
DR   SMART; SM00292; BRCT; 1.
DR   SMART; SM00278; HhH1; 4.
DR   SMART; SM00532; LIGANc; 1.
DR   SUPFAM; SSF52113; BRCT; 1.
DR   SUPFAM; SSF50249; Nucleic_acid_OB; 1.
DR   SUPFAM; SSF47781; RuvA_2_like; 1.
DR   TIGRFAMs; TIGR00575; Dnlj; 1.
DR   PROSITE; PS50172; BRCT; 1.
DR   PROSITE; PS01055; DNA_LIGASE_N1; 1.
DR   PROSITE; PS01056; DNA_LIGASE_N2; 1.
DR   HOGENOMDNA; ETHAR1_1.PE1002; -.
KW   Complete proteome; DNA damage; DNA repair; DNA replication; Ligase;
KW   NAD.
SQ   SEQUENCE   661 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDAAARAKEL RKALSRHNYL YYVLDAPEIE DFEYDRMLRE LEELEAAHPE IVTPDSPTQR
     VGGEAVGQFE PVRHEVPMES LQDVFSVEEV RAFDERMHAA LSTVRYAVEP KIDGLSVALE
     YRNGLFVRGS TRGDGVTGED VTANLRTVRS IPLRLSRPLP FLEVRGEVFM PVAKFEALVR
     AQELREEKLF KNPRNAAAGS LRQKNPKITS ARGLDIFVFN IQRIEGATVE SHLAGHALLK
     ELGFKVVAHT ACDTLEKTET EITRIGESRG SLPYGIDGAV VKVDDFTARR MLGSTAKFPR
     WAVAFKFPPE EKRTGLLSID INVGRTGALT PTAVLEPVLL AGSTVARASL HNEDFIREKD
     IRIGDTVVVR KAGDIIPEIV SVAEHGGGKP YRMPTACPSC GAPVAREKDE AVLRCQNPDC
     PAQLLRHLIH FASRDAMDIE GMGPALVESL VGEGLVRSIA DVYDLNAEAV AKLERMGKKS
     AENLIAAIET SKRAGLARLL YALGVRQVGQ KAAGLIAARF GSMERLFSAT EDELCAIDEI
     GGIIAENVVR FFALEDTARL VERLRAAGVD LTAREQEVAD TRLSGQIFVL TGTLSKYSRE
     EAKKRIEALG GKVTGSVSKK TSYVVAGEEA GSKLDKALAL GVPVLDEAAF EQLLGISETE
     E
//

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