(data stored in SCRATCH3701 zone)

HOGENOM6: ETHAR1_1_PE7

ID   ETHAR1_1_PE7                         STANDARD;      PRT;   846 AA.
AC   ETHAR1_1_PE7; E6U5D1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (ETHAR1_1.PE7).
GN   OrderedLocusNames=Ethha_0007;
OS   ETHANOLIGENENS HARBINENSE YUAN-3.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae;
OC   Ethanoligenens.
OX   NCBI_TaxID=663278;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS ETHAR1_1.PE7.
CC       Ethanoligenens harbinense YUAN-3 chromosome, complete genome.
CC       pEp5, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E6U5D1_ETHHY
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E6U5D1; -.
DR   EMBL; CP002400; ADU25598.1; -; Genomic_DNA.
DR   RefSeq; YP_004090329.1; NC_014828.1.
DR   GeneID; 10090944; -.
DR   GenomeReviews; CP002400_GR; Ethha_0007.
DR   KEGG; eha:Ethha_0007; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; ETHAR1_1.PE7; -.
DR   PRODOM; ETHAR1_1_PE7.
DR   SWISS-2DPAGE; ETHAR1_1_PE7.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   846 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNFDGQKLIP VEIREEMEKS FLEYSMSVIV SRALPDVRDG LKPVHRRILY AMYEDNLLPT
     NAYRKSATTV GNVLGRYHPH GDASVYDALV RMAQSFSLRY PLVDGHGNFG SIDGDGPAAY
     RYTEARMSRI SLEMLQDIEK ETVDFQPNFD DVRKEPIVIP SRFPNILVNG SSGIAVGMAT
     NIPPHNLGEV IDGMALLIDN PDATLEELTA HIQGPDFPTG GIIMGRAGIR EAYVKGRSRI
     TLRAKATIEE DDNGRSRIIV TEIPYMVSKA RIVEGIAELH KEKRIEGISD LRDESDREGL
     RIVVELKRDA NPQVVLNRLY TYSQLQETVP VIMLALVNGH PRVLPLRDIL TEYIHFQEQV
     VTRRTQYDLR KAEERAHILE GLKIALDFID EVIRILRASK SIPEGKAALM ERFELDDIQA
     QAIVQMRLGQ LTNLEREKIE EELAALETKI ANFKAILADE QRILQIVKEE ALEVKAKFGD
     ERRTRIENVS GEVDVEDLIP VEDVVLTLTN FGYIKRLPAA AYHSQRRGGR GVNGLTRREE
     DVARELFVCS THDFVLFFTS HGRCYRLKGY EVPEGSRTSK GMNVANILPV AQDENITAMI
     KVPKFEEDCY LVMVTKKGIV KRTSLKEYDT ARKAGVIGIL LEEDDELVGV LLTDGSAHIL
     VGTRNGVAIR FVETDARPMG RAAHGVKAIS LEGGDYVVGV TVPNGAGSLL LITENGYGKR
     VPFEDFRVQN RGGKGLTSYN INEKTGPVAG LRVVEESDDA LFISSDGVVI RVPVAEIPVY
     SRYAQGVRVM RVGEETKVVT VTSAAHEEES EEESETSPED AEQPETETAE NSEKPDGGST
     DNKPQS
//

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