(data stored in SCRATCH3701 zone)

HOGENOM6: EUBLK_1_PE10

ID   EUBLK_1_PE10                         STANDARD;      PRT;   834 AA.
AC   EUBLK_1_PE10; E3GHQ6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; (EUBLK_1.PE10).
GN   OrderedLocusNames=ELI_0010;
OS   EUBACTERIUM LIMOSUM KIST612.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=903814;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS EUBLK_1.PE10.
CC       Eubacterium limosum KIST612 chromosome, complete genome.
CC       pEp5, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E3GHQ6_EUBLK
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E3GHQ6; -.
DR   EMBL; CP002273; ADO35035.1; -; Genomic_DNA.
DR   RefSeq; YP_003957998.1; NC_014624.1.
DR   GeneID; 9881911; -.
DR   GenomeReviews; CP002273_GR; ELI_0010.
DR   KEGG; elm:ELI_0010; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; EUBLK_1.PE10; -.
DR   PRODOM; EUBLK_1_PE10.
DR   SWISS-2DPAGE; EUBLK_1_PE10.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   834 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDEIIEYDRI KEVNIEEEMK SCYVDYAMSV IIGRALPDVR DGLKPVHRRI LYAMSELGMT
     PDKPTRKSAR IVGEVLGKYH PHGDTAVYDA MVRMAQEFST RYMTIYGQGN FGSIDGDGAA
     AMRYTEAKMS KIALEMLRDI NKDTVDFIPN FDESEMEPEV LPARVPHLLV NGSAGIAVGM
     ATNIPPHNLG EVVDGTIAYI DNPDITIDEL MVHIKGPDFP TAGILLGKSG IKEAYRTGRG
     RIKIRSKVEM ETTKKGRKQI VVTEIPYMVN KSKLVEKIAE LVKEKRVEGI ADLRDETDLK
     KGIRIVIELK RDANETIILN QLYKHTQLQD TFGVIMLALV GNEYDKKKLE PKVLNLKQVL
     HYYVEHQKEI ITRRTIFDLK KAEARAHILE GLRIALDNID EVIALIRAAK DGKEAKVQLM
     ERFALTEIQA QAILDMRLQR LTGLEREKIE EEYAELQKMI AEYKAILADE QLVLNIIKDE
     LTEIKEKYGD ERRTSFDIDV EDFDVEDLIE EEEVVITMTH IGYVKRISAD TYRSQKRGGK
     GITALSTREN DFVEHLFTTT THHFLLFFSN KGKVYRLKAF EVPEGGRTAR GTAIVNILQL
     DPDEKITTMI PVKEFTADKC LIMATKQGII KKTDLTEYDS SRKNGIIGIN LREGDELINV
     RLVEENEDIV MGTQKGYAIR FTSKEVRPLK RTSIGVRGIE LRDDDVVVGM DIVSDDLFVL
     CVSDNGYGKL TSGDQYRSQK RGGKGVQTYK VTKKTGELVG FCVISRDGEI MMINNQGVVI
     KLEGNDISTV GRNTQGVRLM KLQAGEQIAT ISKVYKEDPE EDIEDGQVSI LDEK
//

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