(data stored in ACNUC7421 zone)

HOGENOM: EXIS2_3_PE1

ID   EXIS2_3_PE1                          STANDARD;      PRT;   464 AA.
AC   EXIS2_3_PE1; B1YGB2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (EXIS2_3.PE1).
GN   Name=dnaA; OrderedLocusNames=Exig_0001;
OS   EXIGUOBACTERIUM SIBIRICUM 255-15.
OC   Bacteria; Firmicutes; Bacillales; Bacillales Family XII. Incertae Sedis;
OC   Exiguobacterium.
OX   NCBI_TaxID=262543;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS EXIS2_3.PE1.
CC       Exiguobacterium sibiricum 255-15 chromosome, complete genome.
CC       pEp5, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:DNAA_EXIS2
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B1YGB2; -.
DR   EMBL; CP001022; ACB59489.1; -; Genomic_DNA.
DR   RefSeq; YP_001812506.1; NC_010556.1.
DR   ProteinModelPortal; B1YGB2; -.
DR   STRING; B1YGB2; -.
DR   GeneID; 6175617; -.
DR   GenomeReviews; CP001022_GR; Exig_0001.
DR   KEGG; esi:Exig_0001; -.
DR   OMA; SKMYSSV; -.
DR   ProtClustDB; PRK00149; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; EXIS2_3.PE1; -.
KW   chromosomal replication initiator protein DnaA;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
SQ   SEQUENCE   464 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKNAAELWHN VLSVIEEEQR TPKASYDMWL KSTEGVTLNG TTLIVSAPAA FTVTWLERQY
     LSLLEDTVEE VTGSRLDIQF IEEGQAKHML DRQNEEVEVM EVAPAKTKAQ KTPKSSDELV
     MSELGQLNEK YTFDTFVIGS GNRFAHAASL AVAEAPAKAY NPLFIYGGVG LGKTHLMHAI
     GQYVQDQKLG TKIAYVSSEQ FTNDFINSIR DNKTVQFRNK YRNIDVLLID DIQFLAGKEQ
     TQEEFFHTFN ALHNDQKQII ISSDRPPKEI PTLEDRLRSR FEWGLITDIT PPDLETRIAI
     LRKKANAEQL DVSNEVMLYI ASQIDTNIRE LEGALTRVIA YANLVGRTID PNVAAEALHN
     IMPASEPRKV TIRDIQESVS KHFNLPFDDL KAKKRTKSIA FPRQIAMYLS REMTESSLPK
     IGEEFGGRDH TTVIHAHEKI STLVKSDGET GKVIEQIKHE LKHS
//

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