(data stored in SCRATCH3701 zone)

HOGENOM6: EXIS2_3_PE6

ID   EXIS2_3_PE6                          STANDARD;      PRT;   886 AA.
AC   EXIS2_3_PE6; B1YGB7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (EXIS2_3.PE6).
GN   OrderedLocusNames=Exig_0006;
OS   EXIGUOBACTERIUM SIBIRICUM 255-15.
OC   Bacteria; Firmicutes; Bacillales; Bacillales Family XII. Incertae Sedis;
OC   Exiguobacterium.
OX   NCBI_TaxID=262543;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS EXIS2_3.PE6.
CC       Exiguobacterium sibiricum 255-15 chromosome, complete genome.
CC       pEp5, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:B1YGB7_EXIS2
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B1YGB7; -.
DR   EMBL; CP001022; ACB59494.1; -; Genomic_DNA.
DR   RefSeq; YP_001812511.1; NC_010556.1.
DR   ProteinModelPortal; B1YGB7; -.
DR   SMR; B1YGB7; 30-487.
DR   STRING; B1YGB7; -.
DR   GeneID; 6175521; -.
DR   GenomeReviews; CP001022_GR; Exig_0006.
DR   KEGG; esi:Exig_0006; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; EXIS2_3.PE6; -.
DR   PRODOM; EXIS2_3_PE6.
DR   SWISS-2DPAGE; EXIS2_3_PE6.
KW   DNA gyrase, A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   886 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDQQGIIKD INISQEMRTS FMDYAMSVIV ARALPDVRDG LKPGHRRILY AMNDLGIRAD
     KPHKKSARIV GEVIGKYHPH GDSAVYDTMV RMAQDFSYRY ELVDGHGNFG SVDGDSAAAM
     RYTEARMSKI AMEIVRDINK NTVNFKDNYD GSEREPEVLP SRFPNLLVNG SSGIAVGMAT
     NIPPHQLGEV IDGVLALSHN PDITISELMQ HIPGPDFPTA GEILGRSGIR RAYETGRGSL
     IVRAKAEIEQ TKKDRERIIV TELPYQVNKA RLVEKIADLV REKKIEGITD LRDESDRRGM
     RVVMEIRRDA NASVILNNLY KQTSMQTTFG VNMLAIVSGR PRTLTLKEML YHYLEHQKEI
     VRRRTQFDLE KAEAREHLLA GLRIALDHLD EVIKIIRANR TADAAREQLM ERFELSEKQS
     QAILDMRLQR LTGLEREKID AEYDEIMALI TELKRILESD EVLLELIRTE LEEVKERFND
     QRRTEIRMDH IEFEDEDLIP EKDIIITLTS SGYIKRLTTD SYRAQRRGGR GVQGIGTNDA
     DYVTRLLSCS THDTILFFTN RGKVYRIRGY EVPEMSRTSK GVPIINLIQI ERDEKVETMI
     PVNFKRYLEE QEAAEATENI IDVEVTAEDA PDGLEEPEEA LDAEEVMQDE QKSLIFMTRK
     GRVKRSPLSA YARINKNGLI AIRLFEDDEL TSVRLASTED EVFTVSNTGK AIRFPITNVR
     SMGRGARGVK AMNLSADAIV IGMELARDEQ DVLVITEKGF GKRTPMTEFR TQSRGGKGLI
     ASKVTDRVGQ IVALRIVDVD DDIMIMTESG IVIRTDSQNI SSVGRNAQGV KVIRIEEGDR
     VATVAKLKKE DAVEEEGIVL EEGETGSEEQ PVSTSEMNSE SEQTEE
//

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