(data stored in SCRATCH3701 zone)

HOGENOM6: EXISA_1_PE1716

ID   EXISA_1_PE1716                       STANDARD;      PRT;   855 AA.
AC   EXISA_1_PE1716; C4KZY8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (EXISA_1.PE1716).
GN   OrderedLocusNames=EAT1b_1725;
OS   EXIGUOBACTERIUM SP. AT1B.
OC   Bacteria; Firmicutes; Bacillales; Bacillales Family XII. Incertae Sedis;
OC   Exiguobacterium.
OX   NCBI_TaxID=360911;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS EXISA_1.PE1716.
CC       Exiguobacterium sp. AT1b, complete genome.
CC       pEp5, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:C4KZY8_EXISA
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C4KZY8; -.
DR   EMBL; CP001615; ACQ70651.1; -; Genomic_DNA.
DR   RefSeq; YP_002886096.1; NC_012673.1.
DR   STRING; C4KZY8; -.
DR   GeneID; 7870772; -.
DR   GenomeReviews; CP001615_GR; EAT1b_1725.
DR   KEGG; eat:EAT1b_1725; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; EXISA_1.PE1716; -.
DR   PRODOM; EXISA_1_PE1716.
DR   SWISS-2DPAGE; EXISA_1_PE1716.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   855 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAEQENIKDI NISQEMRTSF MDYAMSVIVS RALPDVRDGL KPVHRRILYA MNELGIRADK
     PHKKSARVVG DVIGKYHPHG DSAVYETMVR MAQDFSYRYE LVDGHGNFGS VDGDSAAAMR
     YTEARMSKIA MELVRDIGKN TIDYQPNFDG EEKEPVVLPA RFPNFLVNGT SGIAVGMATN
     VPPHNLNEVI DGVLALSHNP DITIAELMQH IPGPDFPTAG EILGRSGIRR AYETGRGSIT
     MRAKAEIEVL KNGRERILVH EIPYQVNKAR LVEKIADLVR DKKIEGITDL RDESDRNGMR
     IVIEVRRDAN ASVILNNLYK QTPMQTTFGV NMLALVGGRP KTLNIKQAIY YYIEHQKEVV
     RRRTQFDLDK AEARAHILEG LRVALDHLDE VIAIIRSTRT GDEAREKLIA RFGLSTEQTQ
     AILDMRLQRL TGLEREKIEG EYREVKALIE ELRAILGDEE LLLDIIRNEL IEIKERYGDA
     RRTVIRTDIV ELEDEDLIPV RDMMITLTSE GYIKSIPSDS YRTQRRGGRG KQGMGTNDED
     FVLRLLSAST HDTILFFTNF GRVFRLKGYE IPEMSRTAKG MPIINLLQID KGEKVETMIP
     VDFNSYLANQ TVAEETQDES EEVADEQLSL VFITKEGLIK RSPLSAYARI NKNGLRAISL
     NETDELVTVR LAKSDDEMLI VTRQGMSIRF PLEGEVRSMG RTARGVRAIR LKKEDDLVVS
     MEIVRTTQDV LIITEKGYGK RTAMEQFRTQ GRGGSGIIGI KTDRGTVVGM RVVDEDDDIM
     LMTELGVAIR IDSQTISQMG RSTRGVKVMN IEEGDRLATI AKLKKDELEE ESAVDLENGF
     EDEAPETDES SDVNE
//

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