(data stored in ACNUC31108 zone)

HOGENOM: FELCAGS_4370_2_PE2

ID   FELCAGS_4370_2_PE2                   STANDARD;      PRT;   204 AA.
AC   FELCAGS_4370_2_PE2; P40239;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   Flags: Fragments;
DE   RecName: Full=CD9 antigen;AltName: CD_antigen=CD9; (FELCAGS_4370_2.PE2).
GN   Name=CD9;
OS   FELIS CATUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX   NCBI_TaxID=9685;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS FELCAGS_4370_2.PE2.
CC       Felis catus genescaffold GeneScaffold_4370 CAT partial sequence
CC       1000001..1890066 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:CD9_FELCA
CC   -!- FUNCTION: Involved in platelet activation and aggregation.
CC       Regulates paranodal junction formation. Involved in cell adhesion,
CC       cell motility and tumor metastasis. Required for sperm-egg fusion
CC       (By similarity).
CC   -!- SUBUNIT: Forms both disulfide-linked homodimers and higher
CC       homooligomers as well as heterooligomers with other members of the
CC       tetraspanin family. Associates with CR2/CD21 and with
CC       PTGFRN/CD9P1. Interacts directly with IGSF8 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- PTM: Phosphorylated on tyrosine following B-cell activation (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC   -!- GENE_FAMILY: HOG000230651 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Felis_catus;ENSFCAG00000006863;ENSFCAT00000006865;ENSFCAP00000006372.
DR   EMBL; D30786; - ;
DR   EMBL; L35275; - ;
DR   UniProtKB/Swiss-Prot; P40239; -.
DR   EMBL; L35275; AAA92867.1; -; mRNA.
DR   EMBL; D30786; BAA06452.1; -; mRNA.
DR   RefSeq; NP_001009305.1; NM_001009305.1.
DR   ProteinModelPortal; P40239; -.
DR   STRING; P40239; -.
DR   Ensembl; ENSFCAT00000006865; ENSFCAP00000006372; ENSFCAG00000006863.
DR   GeneID; 493874; -.
DR   CTD; 928; -.
DR   eggNOG; maNOG13559; -.
DR   GeneTree; ENSGT00590000082836; -.
DR   OrthoDB; EOG402WT9; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; ISS:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; ISS:UniProtKB.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; ISS:UniProtKB.
DR   GO; GO:0030913; P:paranodal junction assembly; ISS:UniProtKB.
DR   InterPro; IPR023396; CD81_extracellular.
DR   InterPro; IPR018499; Tetraspanin.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2.
DR   InterPro; IPR000301; Tetraspanin_subgr.
DR   Gene3D; G3DSA:1.10.1450.10; G3DSA:1.10.1450.10; 1.
DR   Pfam; PF00335; Tetraspannin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; Tetraspanin; 1.
DR   PROSITE; PS00421; TM4_1; 1.
DR   HOGENOMDNA; FELCAGS_4370_2.PE2; -.
KW   ENSFCAG000000068635old_1320000031; ENSFCAP000000063721old_1320000031;
KW   D30786; L35275;
KW   Cell adhesion; Disulfide bond; Fertilization; Lipoprotein; Membrane;
KW   Palmitate; Phosphoprotein; Transmembrane; Transmembrane helix.
SQ   SEQUENCE   204 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     LAGIAVLAVG LWLRFDSQTK SIFEQDSQPS SFYTGVYILI GAGALMMLVG FLGCCGAVQE
     SQCMLGLFFG FLLVIFAIEI AAAIWGYSHK DEVIQEVQEF YKDTYNKLKS KDEPQRDTLK
     AIHYALDCCG LAGGVEQFIS DICPQKDILS SITVKPCPEA IKEVFHNKFH IIGAVGIGIA
     VVMIFGMIFS MILCCAIRRS REMV
//

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