(data stored in SCRATCH917 zone)

HOGENOM: FERNB_1_PE1003

ID   FERNB_1_PE1003                       STANDARD;      PRT;   702 AA.
AC   FERNB_1_PE1003; A7HLU3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA topoisomerase; EC=5.99.1 2; (FERNB_1.PE1003).
GN   OrderedLocusNames=Fnod_1027;
OS   FERVIDOBACTERIUM NODOSUM RT17-B1.
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Fervidobacterium.
OX   NCBI_TaxID=381764;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS FERNB_1.PE1003.
CC       Fervidobacterium nodosum Rt17-B1 chromosome, complete genome.
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:A7HLU3_FERNB
CC   -!- FUNCTION: The reaction catalyzed by topoisomerases leads to the
CC       conversion of one topological isomer of DNA to another (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-independent breakage of single-stranded
CC       DNA, followed by passage and rejoining.
CC   -!- SIMILARITY: Belongs to the prokaryotic type I/III topoisomerase
CC       family.
CC   -!- SIMILARITY: Contains 1 Toprim domain.
CC   -!- GENE_FAMILY: HOG000004018 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A7HLU3; -.
DR   EMBL; CP000771; ABS60876.1; -; Genomic_DNA.
DR   RefSeq; YP_001410533.1; NC_009718.1.
DR   ProteinModelPortal; A7HLU3; -.
DR   SMR; A7HLU3; 41-644.
DR   STRING; A7HLU3; -.
DR   GeneID; 5453132; -.
DR   GenomeReviews; CP000771_GR; Fnod_1027.
DR   KEGG; fno:Fnod_1027; -.
DR   eggNOG; COG0550; -.
DR   OMA; WICEREE; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003917; F:DNA topoisomerase type I activity; IEA:EC.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR000380; Topo_IA.
DR   InterPro; IPR003601; Topo_IA_2.
DR   InterPro; IPR023406; Topo_IA_AS.
DR   InterPro; IPR013497; Topo_IA_cen.
DR   InterPro; IPR013824; Topo_IA_cen_sub1.
DR   InterPro; IPR013825; Topo_IA_cen_sub2.
DR   InterPro; IPR023405; Topo_IA_core_domain.
DR   InterPro; IPR003602; Topo_IA_DNA-bd.
DR   InterPro; IPR005733; TopoI_bac-type.
DR   InterPro; IPR006171; Toprim_domain.
DR   Gene3D; G3DSA:1.10.460.10; Topo_IA_cen_sub1; 3.
DR   Gene3D; G3DSA:2.70.20.10; Topo_IA_cen_sub2; 2.
DR   PANTHER; PTHR11390; Topo_IA; 1.
DR   Pfam; PF01131; Topoisom_bac; 1.
DR   Pfam; PF01751; Toprim; 1.
DR   PRINTS; PR00417; PRTPISMRASEI.
DR   SMART; SM00437; TOP1Ac; 1.
DR   SMART; SM00436; TOP1Bc; 1.
DR   SMART; SM00493; TOPRIM; 1.
DR   SUPFAM; SSF56712; Topo_IA_core; 1.
DR   TIGRFAMs; TIGR01051; TopA_bact; 1.
DR   PROSITE; PS00396; TOPOISOMERASE_I_PROK; 1.
DR   HOGENOMDNA; FERNB_1.PE1003; -.
KW   DNA topoisomerase I;
KW   ATP-binding; Complete proteome; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   702 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAKSETKKTT KSSSSNEKAD KTKKKQSQSS SQIIDNSNVS KVIIVESPAK AKTIENILGK
     EYKVISSKGH IRDLPQRDFG VDLKSLDVVF EIIPGKEGVV EQIKNTVKGK EVLLASDPDR
     EGEAIAWHLA TILNINGKNR ITFSEITPKA IQEAVKSPRE IDMKKVNAQL ARRVLDRIVG
     YKISPLLWKI IKDAKSAGRV QSAALKILCE RERERIKFVP QKYYKVWIEI AGLKANLTKI
     GNKKLKPTDI TKEIADDVLK NVKSVNLIDI DVKEVKKNPP LPFITSTLQQ DASSKLGFPV
     AKTMKIAQEL YEGIDTPEGH IAFITYMRTD STRISDEAKE AAKELISKKF GEDYLGDEIR
     KTSKEKSKAK VQDAHECIRP VNVNLLPEEA QKLLDKDHYR LYELIWKRFI ASQMSSAIYK
     QYSYDFKSGD YIFEASIRER IFDGFESVYS TDNEISEEHK ELKIGESYDV LPKTAEAETT
     PPDRYSEASL VKILESEGIG RPSTYATIIQ TLLNRKYIIR NRKTLIPTVL GFVVNDYLEK
     KFPDIVDKGF TAEMEKQLDE IENGTAQWKD VIKNFMKEFG RDLENAGKEF FTINFETNKI
     CETCKEPYHL RVGKYGLYLN CQKCNTNKSV KIDELGVLLE GKMYFIEEKD EKTEDESDTT
     QDEANEKKSG YSSKKNYYRY KTSSRKSAKN QSKQTNKSKK SK
//

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