(data stored in ACNUC7421 zone)

HOGENOM: FRASU_1_PE1004

ID   FRASU_1_PE1004                       STANDARD;      PRT;   595 AA.
AC   FRASU_1_PE1004; E3IYV4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Acetolactate synthase; EC=2.2.1 6; (FRASU_1.PE1004).
GN   OrderedLocusNames=FraEuI1c_1019;
OS   FRANKIA SP. EUI1C.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Frankineae;
OC   Frankiaceae; Frankia.
OX   NCBI_TaxID=298654;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS FRASU_1.PE1004.
CC       Frankia sp. EuI1c chromosome, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:E3IYV4_FRASU
CC   -!- CATALYTIC ACTIVITY: 2 pyruvate = 2-acetolactate + CO(2).
CC   -!- COFACTOR: Binds 1 magnesium ion per subunit (By similarity).
CC   -!- COFACTOR: Binds 1 thiamine pyrophosphate per subunit (By
CC       similarity).
CC   -!- PATHWAY: Amino-acid biosynthesis; L-isoleucine biosynthesis; L-
CC       isoleucine from 2-oxobutanoate: step 1/4.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-valine biosynthesis; L-valine
CC       from pyruvate: step 1/4.
CC   -!- SIMILARITY: Belongs to the TPP enzyme family.
CC   -!- GENE_FAMILY: HOG000258448 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E3IYV4; -.
DR   EMBL; CP002299; ADP79092.1; -; Genomic_DNA.
DR   RefSeq; YP_004014962.1; NC_014666.1.
DR   ProteinModelPortal; E3IYV4; -.
DR   GeneID; 9971442; -.
DR   GenomeReviews; CP002299_GR; FraEuI1c_1019.
DR   KEGG; fri:FraEuI1c_1019; -.
DR   GO; GO:0003984; F:acetolactate synthase activity; IEA:EC.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR012846; Acetolactate_synth_lsu.
DR   InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom.
DR   InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR   InterPro; IPR000399; TPP-bd_CS.
DR   InterPro; IPR011766; TPP_enzyme-bd_C.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   Pfam; PF00205; TPP_enzyme_M; 1.
DR   Pfam; PF02776; TPP_enzyme_N; 1.
DR   TIGRFAMs; TIGR00118; Acolac_lg; 1.
DR   PROSITE; PS00187; TPP_ENZYMES; 1.
DR   HOGENOMDNA; FRASU_1.PE1004; -.
KW   Amino-acid biosynthesis; Branched-chain amino acid biosynthesis;
KW   Complete proteome; Magnesium; Metal-binding; Thiamine pyrophosphate;
KW   Transferase.
SQ   SEQUENCE   595 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTREITGAQS LVHSLEAVGA DVVFGIPGGA ILPAYDPLYD SARVRHILVR HEQGAGHAAE
     GYAQATGKVG VCMATSGPGA TNLVTPIADA YMDSVPMVAI TGQVARPAIG TDAFQEADIC
     GITMPITKHN FLVQSADDIP RTIAEAFHLA ATGRPGPVLV DLPKDVLQSL TAVLPHEVWP
     PTLDLPGYRP VTRPHAKQVR EAAKMISASR RPVLYIGGGV LKSRASAELR ILAELTGIPV
     VTTLMARGAF PDSHHLHLGM PGMHGSVAAV TALQKSDLLI ALGTRFDDRV TGKLSSFAPT
     AQIIHADIDP AEIGKNRVAD VPIVGDCREV IADLIGALQA EPKPDLAGWW DHLNRWRDTY
     PLGFTEPADG SLAPQHVIER IGKIAGPDAI YTAGVGQHQM WAAQFISYEQ PYTFLNSGGA
     GTMGYAVPAA MGAKVGRPEA TVWAIDGDGC FQMTNQELAT CALEGIPIKV AVINNGALGM
     VRQWQTLFYD ERYSNTDLGT HPASSRTGVK RVPDFVRLAE ALGCVGLRCE TAGDVDSTIE
     KAMAIDDAPV VIDFVVHPDA MVWPMVAAGS SNDDIKVARG MAPDFDYSGD AEVNL
//

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