(data stored in SCRATCH3701 zone)

HOGENOM6: FRAT1_1_PE1415

ID   FRAT1_1_PE1415                       STANDARD;      PRT;   868 AA.
AC   FRAT1_1_PE1415; Q14G48;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, subunit A; EC=5.99.1 3; (FRAT1_1.PE1415).
GN   Name=gyrA; OrderedLocusNames=FTF1575c;
OS   FRANCISELLA TULARENSIS SUBSP. TULARENSIS FSC198.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC   Francisellaceae; Francisella.
OX   NCBI_TaxID=393115;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS FRAT1_1.PE1415.
CC       Francisella tularensis subsp. tularensis FSC198, complete genome.
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:Q14G48_FRAT1
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q14G48; -.
DR   EMBL; AM286280; CAL09591.1; -; Genomic_DNA.
DR   RefSeq; YP_667629.1; NC_008245.1.
DR   ProteinModelPortal; Q14G48; -.
DR   SMR; Q14G48; 30-522, 536-842.
DR   STRING; Q14G48; -.
DR   GeneID; 4200367; -.
DR   GenomeReviews; AM286280_GR; FTF1575c.
DR   KEGG; ftf:FTF1575c; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q14G48; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; FRAT1_1.PE1415; -.
DR   PRODOM; FRAT1_1_PE1415.
DR   SWISS-2DPAGE; FRAT1_1_PE1415.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   868 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSIITKESSS INIEKELKQS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF AMNELSNYYN
     RPYKKSARVV GDVIGKYHPH GDTAVYDTIV RMAQPFSLRY TLVDGQGNFG SVDGDSPAAM
     RYTEIRMEKL THELLIDIDK ETVDFSPNYD NTELVPDVLP TRVPNLLVNG SSGIAVGMAT
     NIPPHNMTEV INGTIALIDN PNLTIEELIE YILAPDFPTG SYINGTDGIL EAYKTGRGRV
     IMRAKADIHE DEASGKAQII VTEIPYQVNK AKLVEKIAEL VKDKKVAGIS ELRDESDKDG
     IRVVIDLKRD ESPEVVLNTL YAQTQLQCSF GINMVALSDN RPKLLNLKEI LEQFIKHRKE
     VVTRRTIFEL RKSKERAHIL EGLLLSLANI DEMIKLIKAS PSPADAKESM LARSWNGSMV
     KSMLEGVDVK MYRKETLASH YGIQVDSSYN LTEEQADAIL ALRLHRLTGL EQDKIVNEFK
     ELIDRVKYLI SILSDIKELI RVVKDELVEI RDNYGDQRKS EIIESRLDLT REDLIAEEDM
     VVTLSMDGYV KTQPLSMYNA QKRGGVGKSA TKTKEEDSIF KLMLASTHDT MLCFSSLGRV
     YWSKVYDFPV ASRISKGRPI NNILPLEKDE RITAMMPISQ FNEGWYVFMA TKLGRVKKVD
     LSEFARPRSK GKIAIGLNDG DELSYVALTD GNKQIMMFSD AGKAIRFDES DVRAMGRSAA
     GVTGMRLHHN QKIVSVIVTN PDEGIVLAAT ENGYGKRTAV SEYRKTKRAS QGVIAISTSE
     RNGKVVVAVL VENDEDIVMI TDNGTLVRTS SDEVRECGRS AQGVRLINLR NNEKLISLKV
     VKQDDVEDNQ DIENNEDIES SDVTVQSE
//

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