(data stored in ACNUC7421 zone)

HOGENOM: FRATN_1_PE1001

ID   FRATN_1_PE1001                       STANDARD;      PRT;   216 AA.
AC   FRATN_1_PE1001; A0Q6P7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Holliday junction ATP-dependent DNA helicase ruvA; EC=3.6.4
DE   12; (FRATN_1.PE1001).
GN   Name=ruvA; OrderedLocusNames=FTN_1025;
OS   FRANCISELLA NOVICIDA U112.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC   Francisellaceae; Francisella.
OX   NCBI_TaxID=401614;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS FRATN_1.PE1001.
CC       Francisella tularensis subsp. novicida U112, complete genome.
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:RUVA_FRATN
CC   -!- FUNCTION: The ruvA-ruvB complex in the presence of ATP renatures
CC       cruciform structure in supercoiled DNA with palindromic sequence,
CC       indicating that it may promote strand exchange reactions in
CC       homologous recombination. RuvAB is an helicase that mediates the
CC       Holliday junction migration by localized denaturation and
CC       reannealing. RuvA stimulates, in the presence of DNA, the weak
CC       ATPase activity of ruvB (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC   -!- SUBUNIT: Forms a complex with ruvB (By similarity).
CC   -!- SIMILARITY: Belongs to the ruvA family.
CC   -!- GENE_FAMILY: HOG000057116 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A0Q6P7; -.
DR   EMBL; CP000439; ABK89912.1; -; Genomic_DNA.
DR   RefSeq; YP_898666.1; NC_008601.1.
DR   ProteinModelPortal; A0Q6P7; -.
DR   STRING; A0Q6P7; -.
DR   GeneID; 4548307; -.
DR   GenomeReviews; CP000439_GR; FTN_1025.
DR   KEGG; ftn:FTN_1025; -.
DR   eggNOG; COG0632; -.
DR   OMA; FRERILF; -.
DR   ProtClustDB; PRK00116; -.
DR   BioCyc; FTUL401614:FTN_1025-MON; -.
DR   GO; GO:0009379; C:Holliday junction helicase complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009378; F:four-way junction helicase activity; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR   HAMAP; MF_00031; DNA_helic_RuvA; 1; -.
DR   InterPro; IPR011114; DNA_helicas_Holl-junc_RuvA_C.
DR   InterPro; IPR013849; DNA_helicase_Holl-junc_RuvA_I.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR016027; NA-bd_OB-fold-like.
DR   InterPro; IPR000085; RuvA.
DR   InterPro; IPR010994; RuvA_2-like.
DR   Gene3D; G3DSA:2.40.50.140; OB_NA_bd_sub; 1.
DR   Pfam; PF07499; RuvA_C; 1.
DR   Pfam; PF01330; RuvA_N; 1.
DR   SMART; SM00278; HhH1; 2.
DR   SUPFAM; SSF50249; Nucleic_acid_OB; 1.
DR   SUPFAM; SSF47781; RuvA_2_like; 1.
DR   SUPFAM; SSF46929; RuvA_C-like; 1.
DR   TIGRFAMs; TIGR00084; RuvA; 1.
DR   HOGENOMDNA; FRATN_1.PE1001; -.
KW   Holliday junction DNA helicase RuvA;
KW   ATP-binding; Complete proteome; DNA damage; DNA recombination;
KW   DNA repair; DNA-binding; Helicase; Hydrolase; Nucleotide-binding;
KW   SOS response.
SQ   SEQUENCE   216 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MISFIKGVLI EKDPTALLID VNGIGYEVFV PMTTFYTLGD IDSQVSLYTH FVVREDAQQL
     YGFKSKVDKK VFQELIKVNG IGARTAIAIL SGMDSKTLLH CIENKDYALL ATVPGIGKKT
     AERLVVEIYD KLLKMANEIY AQTSGTTTTS QDSQAQQAPT SAVLANSIFN ESVDALLALG
     YKQKDAEKMS RSAMGDATTA AEVIRKALQG SIRSKR
//

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