(data stored in SCRATCH zone)

HOGENOM: FUNUC1_1_PE100

ID   FUNUC1_1_PE100                       STANDARD;      PRT;   640 AA.
AC   FUNUC1_1_PE100; Q8R6G8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Bifunctional
DE   glycosyltransferase/methyltransferase;Includes: RecName: Full=KdtA
DE   protein homolog; EC=2.-.-.-;Includes: RecName: Full=tRNA (FUNUC1_1.PE100)
DE   (guanine-N(7)-)-methyltransferase; EC=2.1.1 33; AltName:
DE   Full=tRNA(m7G46)-methyltransferase; .
GN   Name=trmB; OrderedLocusNames=FN1606;
OS   FUSOBACTERIUM NUCLEATUM SUBSP. NUCLEATUM ATCC 25586.
OC   Bacteria; Fusobacteria; Fusobacteriales; Fusobacteriaceae; Fusobacterium.
OX   NCBI_TaxID=190304;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS FUNUC1_1.PE100.
CC       Fusobacterium nucleatum subsp. nucleatum ATCC 25586 chromosome, complet
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:TRMB_FUSNN
CC   -!- FUNCTION: Catalyzes the formation of N(7)-methylguanine at
CC       position 46 (m7G46) in tRNA (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-
CC       homocysteine + tRNA containing N(7)-methylguanine.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the
CC       glycosyltransferase 1 family.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the
CC       methyltransferase superfamily. TrmB family.
CC   -!- GENE_FAMILY: HBG000000000 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q8R6G8; -.
DR   EMBL; AE009951; AAL93721.1; -; Genomic_DNA.
DR   RefSeq; NP_602422.1; NC_003454.1.
DR   ProteinModelPortal; Q8R6G8; -.
DR   CAZy; GT30; Glycosyltransferase Family 30.
DR   GeneID; 992776; -.
DR   GenomeReviews; AE009951_GR; FN1606.
DR   KEGG; fnu:FN1606; -.
DR   NMPDR; fig|190304.1.peg.101; -.
DR   BioCyc; FNUC190304:FN1606-MON; -.
DR   GO; GO:0005529; F:sugar binding; IEA:InterPro.
DR   GO; GO:0008176; F:tRNA (guanine-N7-)-methyltransferase activity; IEA:EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   HAMAP; MF_01057; tRNA_methyltr_TrmB; 1; fused.
DR   InterPro; IPR007507; Glycos_transf_N.
DR   InterPro; IPR003358; tRNA_(Gua-N-7)_MeTrfase.
DR   Pfam; PF04413; Glycos_transf_N; 1.
DR   Pfam; PF02390; Methyltransf_4; 1.
DR   TIGRFAMs; TIGR00091; TIGR00091; 1.
DR   HOGENOMDNA; FUNUC1_1.PE100; -.
KW   3-deoxy-D-manno-octulosonic-acid transferase;
KW   Complete proteome; Methyltransferase; Reference proteome;
KW   S-adenosyl-L-methionine; Transferase; tRNA processing.
SQ   SEQUENCE   640 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MYNLLRKIAL TLYRPFMKEK MKTFINKRLS QDFSDLKDEE YIWIHCSSVG EVNLSEDLVK
     KFYSISRKNI LISVFTDTGY ENAVKKYSDK KKIKVIYFPV DDKKKINEIL NKIKLKLLVL
     VETELWPNLI NEVNEKNSRI IVVNGRISDR SYPRYKKLKF LLKSMLQKIA FFYMQSEIDK
     ERIVSLGAIK EKVENVGNLK FSISLEKYSD IEKKEYRKFL NIGDRKVFVA GSTRTGEDEI
     ILDVFKRLKN YVLIIVPRHL DRLPKIENLI KENNLTYVKY SDLENNTSTG KENIILVDKM
     GVLRKLYSIS DIAFVGGTLV NIGGHNLLEP LFYRKTVIFG KYTQNVVDIA KEILRRKIGF
     QVENVEEFVK AIETIENEKN SDEEINSFFE ENRLIALNIV KKENLIMNNI KEEAKDLWKH
     FFHSEKSNYN MYMYKLLDYP EYIMYDNDVM KEKKSKWSEY FGNSDQIAVE IGTGSGNFIY
     QLAERNPNKN FIGLELRFKR LVLAAQKCKK RNIKNVAFLR KRGEELEDFL ANNEISEMYI
     NFPDPWEGTE KNRIIQERLF KTLDKIMKKD GMLYFKTDHD VYYNDVLELV KTLDNYEVIY
     HTSDLHNSEK AENNIKTEFE QLFLHKHNKN INYIEIKKIV
//

If you have problems or comments...

PBIL Back to PBIL home page