(data stored in SCRATCH zone)

HOGENOM: FUNUC1_1_PE1003

ID   FUNUC1_1_PE1003                      STANDARD;      PRT;   259 AA.
AC   FUNUC1_1_PE1003; P58884;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Dihydroorotate dehydrogenase B (FUNUC1_1.PE1003) (NAD(+)),
DE   electron transfer subunit;AltName: Full=Dihydrdoorotate oxidase B,
DE   electron transfer subunit; .
GN   Name=pyrK; OrderedLocusNames=FN0423;
OS   FUSOBACTERIUM NUCLEATUM SUBSP. NUCLEATUM ATCC 25586.
OC   Bacteria; Fusobacteria; Fusobacteriales; Fusobacteriaceae; Fusobacterium.
OX   NCBI_TaxID=190304;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS FUNUC1_1.PE1003.
CC       Fusobacterium nucleatum subsp. nucleatum ATCC 25586 chromosome, complet
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:PYRK_FUSNN
CC   -!- FUNCTION: Responsible for channeling the electrons from the
CC       oxidation of dihydroorotate from the FMN redox center in the PyrD
CC       type B subunit to the ultimate electron acceptor NAD(+) (By
CC       similarity).
CC   -!- COFACTOR: Binds 1 2Fe-2S cluster per subunit (By similarity).
CC   -!- COFACTOR: Binds 1 FAD per subunit (By similarity).
CC   -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo
CC       pathway; orotate from (S)-dihydroorotate (NAD(+) route): step 1/1.
CC   -!- SUBUNIT: Heterotetramer of 2 PyrK and 2 PyrD type B subunits (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the PyrK family.
CC   -!- SIMILARITY: Contains 1 FAD-binding FR-type domain.
CC   -!- GENE_FAMILY: HOG000225118 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P58884; -.
DR   EMBL; AE009951; AAL94626.1; -; Genomic_DNA.
DR   RefSeq; NP_603327.1; NC_003454.1.
DR   ProteinModelPortal; P58884; -.
DR   GeneID; 991788; -.
DR   GenomeReviews; AE009951_GR; FN0423.
DR   KEGG; fnu:FN0423; -.
DR   NMPDR; fig|190304.1.peg.1006; -.
DR   OMA; EYIASHA; -.
DR   BioCyc; FNUC190304:FN0423-MON; -.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
DR   GO; GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   HAMAP; MF_01211; DHODB_Fe-S_bind; 1; -.
DR   InterPro; IPR012165; Cyt_c3_hydrogenase_gsu.
DR   InterPro; IPR019480; Dihydroorotate_DH_Fe-S-bd.
DR   InterPro; IPR023469; Dihydroorotate_DHASE_ETsu.
DR   InterPro; IPR017927; Fd_Rdtase_FAD-bd.
DR   InterPro; IPR008333; OxRdtase_FAD-bd_dom.
DR   InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   Gene3D; G3DSA:2.10.240.10; G3DSA:2.10.240.10; 1.
DR   Pfam; PF10418; DHODB_Fe-S_bind; 1.
DR   Pfam; PF00970; FAD_binding_6; 1.
DR   Pfam; PF00175; NAD_binding_1; 1.
DR   PIRSF; PIRSF006816; Cyc3_hyd_g; 1.
DR   SUPFAM; SSF63380; Riboflavin_synthase_like_b-brl; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
DR   HOGENOMDNA; FUNUC1_1.PE1003; -.
KW   2Fe-2S; Complete proteome; Electron transport; FAD; Flavoprotein;
KW   Iron; Iron-sulfur; Metal-binding; Pyrimidine biosynthesis;
KW   Reference proteome; Transport.
SQ   SEQUENCE   259 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKIEDCTVEE NVQIAKDTYK MKIKGNFVKE CRTPGQFVNI RIGDGREHVL RRPISISEID
     RGENLVTIIY RIVGEGTKFM ANIKKGNEID VMGPLGRGYD VLSLTKEQTA LLVGGGIGVP
     PLYELAKQFN KRGIKTIIIL GFNSKDEVFY EDEFKKFGET YVSTIDGSVG TKGFVTDVIK
     KLQAENNLVF DKYYSCGPVP MLKALVNAVG EDGYISLENR MACGIGACYA CVCKKKKKDD
     YTRVCYDGPV YLASDVEIE
//

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