(data stored in SCRATCH zone)

HOGENOM: FUNUC1_1_PE1006

ID   FUNUC1_1_PE1006                      STANDARD;      PRT;   237 AA.
AC   FUNUC1_1_PE1006; Q8RG83;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Orotidine 5'-phosphate decarboxylase; EC=4.1.1 23;AltName:
DE   Full=OMP decarboxylase; Short=OMPDCase; Short=OMPdecase;
DE   (FUNUC1_1.PE1006).
GN   Name=pyrF; OrderedLocusNames=FN0426;
OS   FUSOBACTERIUM NUCLEATUM SUBSP. NUCLEATUM ATCC 25586.
OC   Bacteria; Fusobacteria; Fusobacteriales; Fusobacteriaceae; Fusobacterium.
OX   NCBI_TaxID=190304;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS FUNUC1_1.PE1006.
CC       Fusobacterium nucleatum subsp. nucleatum ATCC 25586 chromosome, complet
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:PYRF_FUSNN
CC   -!- FUNCTION: Catalyzes the decarboxylation of orotidine 5'-
CC       monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: Orotidine 5'-phosphate = UMP + CO(2).
CC   -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo
CC       pathway; UMP from orotate: step 2/2.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the OMP decarboxylase family. Type 1
CC       subfamily.
CC   -!- GENE_FAMILY: HOG000226071 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q8RG83; -.
DR   EMBL; AE009951; AAL94629.1; -; Genomic_DNA.
DR   RefSeq; NP_603330.1; NC_003454.1.
DR   ProteinModelPortal; Q8RG83; -.
DR   GeneID; 992754; -.
DR   GenomeReviews; AE009951_GR; FN0426.
DR   KEGG; fnu:FN0426; -.
DR   NMPDR; fig|190304.1.peg.1009; -.
DR   OMA; TVHAYPQ; -.
DR   ProtClustDB; PRK00230; -.
DR   BioCyc; FNUC190304:FN0426-MON; -.
DR   GO; GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
DR   GO; GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.
DR   GO; GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_01200_B; OMPdecase_type1_B; 1; -.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR014732; OMPdecase.
DR   InterPro; IPR018089; OMPdecase_AS.
DR   InterPro; IPR001754; OMPdeCOase_dom.
DR   InterPro; IPR011060; RibuloseP-bd_barrel.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   Pfam; PF00215; OMPdecase; 1.
DR   SMART; SM00934; OMPdecase; 1.
DR   SUPFAM; SSF51366; RibP_bind_barrel; 1.
DR   TIGRFAMs; TIGR01740; PyrF; 1.
DR   PROSITE; PS00156; OMPDECASE; 1.
DR   HOGENOMDNA; FUNUC1_1.PE1006; -.
KW   orotidine 5'-phosphate decarboxylase;
KW   Complete proteome; Decarboxylase; Lyase; Pyrimidine biosynthesis;
KW   Reference proteome.
SQ   SEQUENCE   237 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKKEVIIALD FPTLEKTLEF LDKFKEEKLF VKVGMELYLQ NGPIVIDEIK KRGHKIFLDL
     KLHDIPNTVY SAVKGLAKFN IDILTVHAAG GSEMLKGAKR AMTEAGVNTK VIAITQLTST
     SEEDMRKEQN IQTSIEESVL NYARLAKESG VDGVVSSVLE TKKIREQSGE EFIIINPGIR
     LAEDSKGDQK RVATPIDANR DGASYIVVGR SITGNENPEE RYRLIKNMFE MGDKYVE
//

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