(data stored in SCRATCH zone)

HOGENOM: FUNUC1_1_PE1007

ID   FUNUC1_1_PE1007                      STANDARD;      PRT;   211 AA.
AC   FUNUC1_1_PE1007; P58856;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Orotate phosphoribosyltransferase; Short=OPRT;
DE   Short=OPRTase; EC=2.4.2 10; (FUNUC1_1.PE1007).
GN   Name=pyrE; OrderedLocusNames=FN0427;
OS   FUSOBACTERIUM NUCLEATUM SUBSP. NUCLEATUM ATCC 25586.
OC   Bacteria; Fusobacteria; Fusobacteriales; Fusobacteriaceae; Fusobacterium.
OX   NCBI_TaxID=190304;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS FUNUC1_1.PE1007.
CC       Fusobacterium nucleatum subsp. nucleatum ATCC 25586 chromosome, complet
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:PYRE_FUSNN
CC   -!- FUNCTION: Catalyzes the transfer of a ribosyl phosphate group from
CC       5-phosphoribose 1-diphosphate to orotate, leading to the formation
CC       of orotidine monophosphate (OMP) (By similarity).
CC   -!- CATALYTIC ACTIVITY: Orotidine 5'-phosphate + diphosphate = orotate
CC       + 5-phospho-alpha-D-ribose 1-diphosphate.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo
CC       pathway; UMP from orotate: step 1/2.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine
CC       phosphoribosyltransferase family. PyrE subfamily.
CC   -!- GENE_FAMILY: HOG000037975 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; P58856; -.
DR   EMBL; AE009951; AAL94630.1; -; Genomic_DNA.
DR   RefSeq; NP_603331.1; NC_003454.1.
DR   ProteinModelPortal; P58856; -.
DR   SMR; P58856; 8-209.
DR   GeneID; 991787; -.
DR   GenomeReviews; AE009951_GR; FN0427.
DR   KEGG; fnu:FN0427; -.
DR   NMPDR; fig|190304.1.peg.1010; -.
DR   OMA; LPMTYVR; -.
DR   ProtClustDB; PRK00455; -.
DR   BioCyc; FNUC190304:FN0427-MON; -.
DR   GO; GO:0004588; F:orotate phosphoribosyltransferase activity; IEA:EC.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR   GO; GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_01208; PyrE; 1; -.
DR   InterPro; IPR004467; Or_phspho_trans_clade-1.
DR   InterPro; IPR023031; Orotate_PribosylTferase.
DR   InterPro; IPR000836; PRibTrfase.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   TIGRFAMs; TIGR00336; PyrE; 1.
DR   PROSITE; PS00103; PUR_PYR_PR_TRANSFER; 1.
DR   HOGENOMDNA; FUNUC1_1.PE1007; -.
KW   Complete proteome; Glycosyltransferase; Magnesium;
KW   Pyrimidine biosynthesis; Reference proteome; Transferase.
SQ   SEQUENCE   211 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKWGINMLNR EIINALLDIK AVELRVDKEN WFTWASGIKS PIYCDNRLTM SYPKIRKQIA
     EGFVKKINEL YPNVDYIVGT ATAGIPHAAW ISDIMDLPML YVRGSAKDHG KTNQIEGKFE
     KGKKVVVIED LISTGKSSVL AAQALQEEGL EVLGVIAIFS YNLNKAKEKF DEAKIPFSTL
     TNYDVLLELA KETGLIGDKE NQILIDWRNN L
//

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