(data stored in ACNUC12663 zone)

HOVERGEN: GAGD3_HUMAN

ID   GAGD3_HUMAN             Reviewed;         111 AA.
AC   Q96GT9; Q5HYR4;
DT   11-JUL-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-NOV-2009, entry version 60.
DE   RecName: Full=G antigen family D member 3;
DE   AltName: Full=Protein XAGE-2;
DE   AltName: Full=Cancer/testis antigen 12.2;
DE            Short=CT12.2;
GN   Name=XAGE2; Synonyms=GAGED3;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX   MEDLINE=22021429; PubMed=11992404; DOI=10.1002/ijc.10371;
RA   Zendman A.J.W., van Kraats A.A., Weidle U.H., Ruiter D.J.,
RA   van Muijen G.N.P.;
RT   "The XAGE family of cancer/testis-associated genes: alignment and
RT   expression profile in normal tissues, melanoma lesions and Ewing's
RT   sarcoma.";
RL   Int. J. Cancer 99:361-369(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15772651; DOI=10.1038/nature03440;
RA   Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA   Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A.,
RA   Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G.,
RA   Jones M.C., Hurles M.E., Andrews T.D., Scott C.E., Searle S.,
RA   Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R.,
RA   Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L.,
RA   Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A.,
RA   Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S.,
RA   Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R.,
RA   Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M.,
RA   Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N.,
RA   Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D.,
RA   Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W.,
RA   Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C.,
RA   Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C.,
RA   Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA   Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA   Corby N., Connor R.E., David R., Davies J., Davis C., Davis J.,
RA   Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S.,
RA   Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I.,
RA   Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L.,
RA   Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P.,
RA   Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S.,
RA   Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A.,
RA   Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J.,
RA   Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J.,
RA   Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S.,
RA   de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z.,
RA   Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C.,
RA   Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W.,
RA   Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA   Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA   McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T.,
RA   Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I.,
RA   Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N.,
RA   Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J.,
RA   Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E.,
RA   Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S.,
RA   Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA   Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA   Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA   Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T.,
RA   Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S.,
RA   Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L.,
RA   Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A.,
RA   Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L.,
RA   Williams G., Williams L., Williamson A., Williamson H., Wilming L.,
RA   Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H.,
RA   Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A.,
RA   Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA   Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A.,
RA   Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T.,
RA   Gibbs R.A., Beck S., Rogers J., Bentley D.R.;
RT   "The DNA sequence of the human X chromosome.";
RL   Nature 434:325-337(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Placenta;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [4]
RP   IDENTIFICATION.
RX   MEDLINE=99211468; PubMed=10197611;
RA   Brinkmann U., Vasmatzis G., Lee B., Pastan I.;
RT   "Novel genes in the PAGE and GAGE family of tumor antigens found by
RT   homology walking in the dbEST database.";
RL   Cancer Res. 59:1445-1448(1999).
CC   -!- SIMILARITY: Belongs to the GAGE family.
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CC   -!- GENE_FAMILY: HBG056227 [ FAMILY / ALN / TREE ]
DR   EMBL; AJ318891; CAC88125.1; -; Genomic_DNA.
DR   EMBL; AJ318892; CAC88125.1; JOINED; Genomic_DNA.
DR   EMBL; AJ318880; CAC83007.1; -; mRNA.
DR   EMBL; BX293536; CAI40835.1; -; Genomic_DNA.
DR   EMBL; AL953874; CAI41681.1; -; Genomic_DNA.
DR   EMBL; BC009232; AAH09232.1; -; mRNA.
DR   EMBL; BC066311; AAH66311.1; -; mRNA.
DR   IPI; IPI00062756; -.
DR   RefSeq; NP_001073006.1; -.
DR   RefSeq; NP_570133.1; -.
DR   UniGene; Hs.522654; -.
DR   IntAct; Q96GT9; 1.
DR   Ensembl; ENST00000286049; ENSP00000286049; ENSG00000155622; Homo sapiens.
DR   Ensembl; ENST00000330906; ENSP00000333775; ENSG00000185751; Homo sapiens.
DR   GeneID; 728242; -.
DR   GeneID; 9502; -.
DR   KEGG; hsa:728242; -.
DR   KEGG; hsa:9502; -.
DR   UCSC; uc004dqe.1; human.
DR   CTD; 728242; -.
DR   CTD; 9502; -.
DR   GeneCards; GC0XM052397; -.
DR   GeneCards; GC0XP052129; -.
DR   H-InvDB; HIX0016746; -.
DR   H-InvDB; HIX0077112; -.
DR   HGNC; HGNC:4112; XAGE2.
DR   MIM; 300416; gene.
DR   PharmGKB; PA28527; -.
DR   HOGENOM; Q96GT9; -.
DR   HOVERGEN; Q96GT9; -.
DR   OMA; ILPKAEH; -.
DR   NextBio; 126585; -.
DR   Bgee; Q96GT9; -.
DR   CleanEx; HS_XAGE2; -.
DR   Genevestigator; Q96GT9; -.
DR   GermOnline; ENSG00000155622; Homo sapiens.
DR   GermOnline; ENSG00000185751; Homo sapiens.
DR   InterPro; IPR008625; GAGE.
DR   Pfam; PF05831; GAGE; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q96GT9.
DR   SWISS-2DPAGE; Q96GT9.
KW   Complete proteome.
FT   DOMAIN        1    108       PRODOM:2005.1:PD012589  18
FT   CHAIN         1    111       G antigen family D member 3.
FT                                /FTId=PRO_0000148350.
SQ   SEQUENCE   111 AA;  12354 MW;  38C93332C5BA0E14 CRC64;
     MSWRGRSTYR PRPRRSLQPP ELIGAMLEPT DEEPKEEKPP TKSRNPTPDQ KREDDQGAAE
     IQVPDLEADL QELCQTKTGD GCEGGTDVKG KILPKAEHFK MPEAGEGKSQ V
//

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